237647
L−(+)-α-Phenylglycine
99%
Synonym(s):
(S)-(+)-2-Phenylglycine, S-(+)-α-Aminophenylacetic acid, L-2-Phenylglycine
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About This Item
Linear Formula:
C6H5CH(NH2)CO2H
CAS Number:
Molecular Weight:
151.16
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-909-8
Beilstein/REAXYS Number:
2208675
MDL number:
Product Name
L−(+)-α-Phenylglycine, 99%
InChI key
ZGUNAGUHMKGQNY-ZETCQYMHSA-N
InChI
1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)/t7-/m0/s1
SMILES string
N[C@H](C(O)=O)c1ccccc1
assay
99%
form
powder
optical activity
[α]20/D +155°, c = 1 in 1 M HCl
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
application(s)
peptide synthesis
Quality Level
Application
Chiral starting material.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Henry Kurniawan et al.
Cell metabolism, 31(5), 920-936 (2020-03-28)
Regulatory T cells (Tregs) maintain immune homeostasis and prevent autoimmunity. Serine stimulates glutathione (GSH) synthesis and feeds into the one-carbon metabolic network (1CMet) essential for effector T cell (Teff) responses. However, serine's functions, linkage to GSH, and role in stress responses in
Aaron D Mills et al.
Bioorganic & medicinal chemistry letters, 20(1), 87-91 (2009-12-04)
A developing therapy of cystic fibrosis caused by the DeltaF508 mutation in CFTR employs correction of defective CFTR chloride channel gating by a 'potentiator' and of defective CFTR protein folding by a 'corrector'. Based on SAR data for phenylglycine-type potentiators
Motohiro Akazome et al.
The Journal of organic chemistry, 75(3), 660-665 (2010-01-07)
In terms of chiral recognition for racemic aryl methyl sulfoxides in the solid state, three kinds of crystalline (S)-alkylglycyl-(S)-phenylglycines were examined as potential dipeptides host molecules. When (S)-alanyl-(S)-phenylglycines [(S,S)-Ala-Phg] crystallized with aryl methyl sulfoxides, the stereochemistry of preferentially included sulfoxides
Jian-Lian Chen et al.
Analytica chimica acta, 718, 130-137 (2012-02-07)
Three different approaches for immobilizing cross-linked chitosan molecules (CS-s) in sol-gel phases to form chiral OT-CEC capillaries were comparatively investigated in this study. To synthesize column I, a bare capillary was first silanized with triethoxysilane (TEOS) and then reacted with
Lu Wang et al.
Enzyme and microbial technology, 51(2), 107-112 (2012-06-06)
α-Amino acid ester hydrolases (AEHs) are enzymes of interest to the semi-synthesis of β-lactam antibiotics with α-amino, such as cephalexin and cefaclor. An undesired side reaction, the hydrolysis of α-amino acid ester, had hindered applications in antibiotics synthesis. Although the
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