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Merck
CN

239798

1,3-Dioxolane

≥99.5%

Synonym(s):

Ethylene glycol methylene ether, Formaldehyde ethylene acetal

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About This Item

Empirical Formula (Hill Notation):
C3H6O2
CAS Number:
Molecular Weight:
74.08
Beilstein:
102453
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay:
≥99.5%
Bp:
75-76 °C/1.013 hPa
Vapor pressure:
70 mmHg ( 20 °C)
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vapor density

2.6 (vs air)

vapor pressure

70 mmHg ( 20 °C)

Assay

≥99.5%

autoignition temp.

525 °F

contains

75 ppm BHT as inhibitor

refractive index

n20/D 1.401 (lit.)

bp

75-76 °C/1.013 hPa

mp

−95 °C (lit.)

density

1.06 g/mL at 25 °C (lit.)

SMILES string

C1COCO1

InChI

1S/C3H6O2/c1-2-5-3-4-1/h1-3H2

InChI key

WNXJIVFYUVYPPR-UHFFFAOYSA-N

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Charles A Ault et al.
Macromolecular rapid communications, 42(5), e2000692-e2000692 (2021-01-28)
Effects of molecular weight of methylphenyl-containing vinylsiloxy-functionalized terpolysiloxanes on their UV-activated crosslinking by hydrosilylation at room temperature in air, shelf life stability of "all-in-one" pastes prepared from them for additive manufacturing, and mechanical properties of the resulting crosslinked elastomers, are
One-step synthesis of 2-alkyl-dioxolanes from ethylene glycol and syngas.
Xiao-Bing Fan et al.
ChemSusChem, 2(10), 941-943 (2009-10-01)
Lukas J Goossen et al.
The Journal of organic chemistry, 73(21), 8631-8634 (2008-10-23)
An efficient synthesis of the angiotensin II receptor antagonist telmisartan is presented involving a decarboxylative cross-coupling of isopropyl phthalate (1) with 2-(4-chlorophenyl)-1,3-dioxolane (2c) as the key step (85% yield). The benzimidazole moiety is constructed regioselectively via a reductive amination-condensation sequence
Silvia Franchini et al.
European journal of medicinal chemistry, 45(9), 3740-3751 (2010-07-08)
A series of 1,3-dioxolane-based compounds incorporating a lactam (2-4) or imide (5-7) moiety was synthesized and the pharmacological profile at alpha(1)-adrenoceptor subtypes and 5-HT(1A) receptor was assessed through binding and functional experiments. Starting from the 2,2-diphenyl-1,3-dioxolane derivative 1, previously shown
Dong Zhou et al.
Nuclear medicine and biology, 35(6), 655-663 (2008-08-06)
Progesterone receptors (PRs) are present in many breast tumors, and their levels are increased by certain endocrine therapies. They can be used as targets for diagnostic imaging and radiotherapy. 16alpha,17alpha-[(R)-1'-alpha-(5-[(76)Br]Bromofurylmethylidene)dioxyl]-21-hydroxy-19-norpregn-4-ene-3,20-dione ([(76)Br]16alpha,17alpha-[(R)-1'-alpha-(5-bromofurylmethylidene)dioxyl]-21-hydroxy-19-norpregn-4-ene-3,20-dione (3)), a PR ligand with relative binding affinity (RBA)=65

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