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Sigma-Aldrich

trans-Cinnamaldehyde

≥99%

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Synonym(s):
trans-3-Phenyl-2-propenal
Linear Formula:
C6H5CH=CHCHO
CAS Number:
14371-10-9
Molecular Weight:
132.16
Beilstein:
1071571
MDL number:
MFCD00007000
PubChem Substance ID:
24854395
NACRES:
NA.22

vapor density

4.6 (vs air)

Quality Level

200

Assay

≥99%

form

liquid

refractive index

n20/D 1.622 (lit.)

bp

250-252 °C (lit.)

mp

−9-−4 °C (lit.)

density

1.05 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

[H]C(=O)\C=C\c1ccccc1

InChI

1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+

InChI key

KJPRLNWUNMBNBZ-QPJJXVBHSA-N

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General description

The neuroprotective and anti-inflammatory effects of trans-cinnamaldehyde (TCA) were studied.

Application

trans-Cinnamaldehyde was used to study the useful amino groups at aminosilanized surface.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H317 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

159.8 °F - closed cup

Flash Point(C)

71 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ji-Hi Pyo et al.
Biological & pharmaceutical bulletin, 36(12), 1928-1935 (2013-12-03)
The anti-inflammatory and neuroprotective effects of trans-cinnamaldehyde (TCA) were investigated on the inflammatory cells and the dopaminergic degeneration in mice. TCA inhibited the up-regulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in the lipopolysaccharide (LPS)-induced inflammatory BV2 microglial
Wen-Xian Du et al.
Journal of agricultural and food chemistry, 60(32), 7799-7804 (2012-07-27)
The addition of plant essential oils to edible films and coatings has been shown to protect against bacterial pathogens and spoilage while also enhancing sensory properties of foods. This study evaluated the effect of adding 0.5 and 0.75% carvacrol (active
Jeyachchandran Visvalingam et al.
Applied and environmental microbiology, 79(3), 942-950 (2012-11-28)
Cinnamaldehyde is a natural antimicrobial that has been found to be effective against many food-borne pathogens, including Escherichia coli O157:H7. Although its antimicrobial effects have been well investigated, limited information is available on its effects at the molecular level. Sublethal
Katherine R Zodrow et al.
Langmuir : the ACS journal of surfaces and colloids, 28(39), 13993-13999 (2012-09-04)
Biofilm-associated infections are one of the leading causes of death in the United States. Although infections may be treated with antibiotics, the overuse of antibiotics has led to the spread of antibiotic resistance. Many natural antimicrobial compounds derived from edible
Amrita A Nagle et al.
PloS one, 7(11), e50125-e50125 (2012-11-28)
Multifunctional trans-cinnamaldehyde (CA) and its analogs display anti-cancer properties, with 2-benzoyloxycinnamaldehyde (BCA) and 5-fluoro-2-hydroxycinnamaldehyde (FHCA) being identified as the ortho-substituted analogs that possess potent anti-tumor activities. In this study, BCA, FHCA and a novel analog 5-fluoro-2-benzoyloxycinnamaldehyde (FBCA), were demonstrated to
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