240230
Phthalimide
≥99%
Synonym(s):
1,3-Dihydro-1,3-dioxoisoindole
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About This Item
Empirical Formula (Hill Notation):
C8H5NO2
CAS Number:
Molecular Weight:
147.13
Beilstein:
118522
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
≥99%
mp
232-235 °C (lit.)
solubility
water: slightly soluble(lit.)
SMILES string
O=C1NC(=O)c2ccccc12
InChI
1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)
InChI key
XKJCHHZQLQNZHY-UHFFFAOYSA-N
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Related Categories
Application
Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
Flash Point(F)
302.0 °F - closed cup
Flash Point(C)
150 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
危险化学品
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Alessio Pierini et al.
Journal of veterinary science, 21(5), e60-e60 (2020-10-06)
Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. The aim of the study was to assess the pharmacokinetics of
Stalin Kondaveeti et al.
Carbohydrate polymers, 106, 365-373 (2014-04-12)
A facile 6-aminoagarose (AA) mediated synthesis of new fluorogenic amides of agarose with nicotinic (AA-NA) and picolinic acids (AA-PA) employing carbodiimide chemistry have been described. 6-Amino agarose (AA) was synthesized in a facile Mitsunobu-inspired microwave mediated method involving the reaction
Heloise Brice et al.
Chemical communications (Cambridge, England), 48(40), 4836-4838 (2012-04-14)
A range of chiral, optically-enriched bicyclic oxabispidines were prepared from (S)-(-)-2,3-epoxypropylphthalimide using an efficient sequence featuring a stereocontrolled intramolecular Mannich reaction as the key transformation.
Kazuaki Ishihara et al.
Organic letters, 10(13), 2893-2896 (2008-06-07)
Catalytic and highly enantioselective Diels-Alder reaction of cyclic and acyclic dienes with alpha-phthalimidoacroleins provides cyclic alpha-quaternary alpha-amino acid precursors. The conformationally flexible chiral ammonium salt of H-L-Phe-L-Leu-N(CH(2)CH(2)) 2-reduced triamine with pentafluorobenzensulfonic acid is very effective as an asymmetric catalyst for
Stanton Hon Lung Kok et al.
Bioorganic & medicinal chemistry, 16(7), 3626-3631 (2008-02-26)
Phthalic anhydride is a highly toxic substance, facing, however, the problem of hydrolysis. In fact, it is rapidly hydrolyzed in aqueous medium, generating phthalic acid as the final product, which is almost harmless to viable cells. Here we describe the
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