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Merck
CN

240699

Epichlorohydrin

≥99%

Synonym(s):

(±)-Epichlorohydrin, (±)-2-(Chloromethyl)oxirane, 1-Chloro-2,3-epoxypropane

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About This Item

Empirical Formula (Hill Notation):
C3H5ClO
CAS Number:
Molecular Weight:
92.52
EC Number:
203-439-8
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
79785
MDL number:
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InChI key

BRLQWZUYTZBJKN-UHFFFAOYSA-N

InChI

1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2

SMILES string

ClCC1CO1

vapor density

3.2 (vs air)

vapor pressure

13.8 mmHg ( 21.1 °C)

assay

≥99%

autoignition temp.

779 °F

expl. lim.

21 %

bp

115-117 °C (lit.)

mp

−57 °C (lit.)

density

1.183 g/mL at 25 °C (lit.)

Application

Employed in the preparation of polyglycidyl ethers and as a cross-linking agent for polymers.
Used in the synthesis of a branched heptaglycerol dendrimer.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

82.4 °F

flash_point_c

28 °C

Regulatory Information

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Chromatographia, 37, 603-603 (1993)
Synlett, 2091-2091 (2007)
Synthesis, 487-487 (1993)
Swetha Inturi et al.
ACS nano, 9(11), 10758-10768 (2015-10-22)
Notwithstanding rapid advances of nanotechnology in diagnostic imaging and drug delivery, the engineered nanocarriers still exhibit substantial lack of hemocompatibility. Thus, when injected systemically, nanoparticles are avidly recognized by blood leukocytes and platelets, but the mechanisms of immune recognition are
An evaluation of the genetic toxicity of epichlorohydrin. A report of an expert group of the International Commission for Protection against Environmental Mutagens and Carcinogens.
R J Srám et al.
Mutation research, 87(3), 299-319 (1981-11-01)

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