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Merck
CN

241067

2-Methoxyethylamine

99%

Synonym(s):

2-Aminoethyl methyl ether

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About This Item

Linear Formula:
CH3OCH2CH2NH2
CAS Number:
Molecular Weight:
75.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-712-1
Beilstein/REAXYS Number:
741854
MDL number:
Assay:
99%
Form:
liquid
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Quality Level

assay

99%

form

liquid

refractive index

n20/D 1.406 (lit.)

bp

95 °C (lit.)

density

0.864 g/mL at 25 °C (lit.)

functional group

amine, ether

SMILES string

COCCN

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

General description

Kinetics of reaction of 2-methoxyethylamine with guanosine 5′-phospho-2-methylimidazolide (2-MeImpG) was studied.

Application

2-Methoxyethylamine can be used as a reactant:
  • In the substitution reaction with phosphoimidazolide-activated derivatives of nucleosides.
  • To synthesize amides by reacting with carboxylic acids.
  • For the chemical modification of α-acrylated cross-linked polymer via aza-Michael addition.


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

53.6 °F

flash_point_c

12 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Mesoporous Structured Silica-An improved catalyst for direct amide synthesis and its application to continuous flow processing.
Comerford J, et al.
ARKIVOC (Gainesville, FL, United States) (2012)
A Kanavarioti et al.
The Journal of organic chemistry, 60(3), 632-637 (1995-02-10)
Aliphatic amines react with phosphoimidazolide-activated derivatives of guanosine and cytidine (ImpN) by replacing the imidazole group. The kinetics of reaction of guanosine 5'-phospho-2-methylimidazolide (2-MeImpG) with glycine ethyl ester, glycinamide, 2-methoxyethylamine, n-butylamine, morpholine, dimethylamine (Me2NH), ethylmethylamine (EtNHMe), diethylamine (Et2NH), pyrrolidine, and
Intrinsic green fluorescent cross-linked poly (ester amide) s by spontaneous zwitterionic copolymerization
Zia A, et al.
Biomacromolecules, 22, 4794-4804 (2021)



Global Trade Item Number

SKUGTIN
241067-50ML04061824485981