251291
β-Glycerophosphate disodium salt hydrate
98%
Synonym(s):
BGP, Glycerol 2-phosphate disodium salt hydrate
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About This Item
Linear Formula:
(HOCH2)2CHOP(O)(ONa)2 · xH2O
CAS Number:
Molecular Weight:
216.04 (anhydrous basis)
UNSPSC Code:
12352103
MDL number:
InChI key
ROPZSVKNEIIIDE-UHFFFAOYSA-L
InChI
1S/C3H9O6P.2Na.H2O/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2
SMILES string
O.[Na+].[Na+].OCC(CO)OP([O-])([O-])=O
assay
98%
mp
102-104 °C (lit.)
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Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.
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