253367
4-(2-Iodoacetamido)-TEMPO
free radical
Synonym(s):
4-(2-Iodoacetamido)-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical, 4-(2-Iodoacetamido)-2,2,6,6-tetramethylpiperidine 1-oxyl
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About This Item
Empirical Formula (Hill Notation):
C11H20IN2O2
CAS Number:
Molecular Weight:
339.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
Form:
solid
form
solid
mp
114-117 °C (lit.)
functional group
amide, iodo
storage temp.
2-8°C
SMILES string
CC1(C)CC(CC(C)(C)N1[O])NC(=O)CI
InChI
1S/C11H20IN2O2/c1-10(2)5-8(13-9(15)7-12)6-11(3,4)14(10)16/h8H,5-7H2,1-4H3,(H,13,15)
InChI key
UCTVRHAKQRFPEZ-UHFFFAOYSA-N
Application
Methionine-specific spin label.
Spin label used to investigate the binding site of phosphoenolpyruvate caboxykinase and GTP, and to evaluate the alkylation of SH1 and SH2 of myosin.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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C Coan et al.
Biochemistry, 21(13), 3214-3220 (1982-06-22)
The labeling kinetics of sarcoplasmic reticulum ATPase with the iodoacetamide spin probe N-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide were followed under conditions designed to selectively label all reactive groups. Approximately 1 mol of spin-label reacted per one 100 000-dalton ATPase chain, indicating only one residue
C Wells et al.
Journal of muscle research and cell motility, 5(1), 97-112 (1984-02-01)
The properties of spin-labelled myosin, prepared from rabbit skeletal and scallop adductor muscle, on forming a long-lived complex with ADP and vanadate (M.ADP.Vi), have been investigated. In the case of an iodoacetamide-based label attached to rabbit myosin or subfragment 1
E Gendek et al.
British journal of industrial medicine, 41(1), 46-50 (1984-02-01)
Alterations in erythrocyte membranes caused by UICC B chrysotile asbestos fibres were studied in red cell ghosts using the spin label technique. The electron paramagnetic resonance (EPR) spectra of two sulphydryl reactive spin labels and one fatty acid spin probe
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 253367-10MG | 04061833278918 |