253421
3-(2-Iodoacetamido)-PROXYL
free radical
Synonym(s):
3-(2-Iodoacetamido)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical
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About This Item
Empirical Formula (Hill Notation):
C10H18IN2O2
CAS Number:
Molecular Weight:
325.17
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
Form:
solid
InChI
1S/C10H18IN2O2/c1-9(2)5-7(12-8(14)6-11)10(3,4)13(9)15/h7H,5-6H2,1-4H3,(H,12,14)
SMILES string
CC1(C)CC(NC(=O)CI)C(C)(C)N1[O]
InChI key
OQIGMSGDHDTSFA-UHFFFAOYSA-N
form
solid
mp
162-164 °C (lit.)
functional group
amide, iodo
storage temp.
2-8°C
Quality Level
General description
3-(2-Iodoacetamido)-PROXYL is a free radical used as a spin probe in spin labeling techniques. This technique is helpful in investigating the dynamic aspects of molecular interactions of substances, proteins, lipids, and cell membranes.
Application
Sulfhydryl group specific spin label. Applications include study of ozone-treated human and bovine erythrocyte membrane proteins and the orientation of myosin subfragment on muscle fibers. DNA fragments containing phosphorothioate diesters can be labeled by spin labels.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Shepherd NE, et al.
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