254088
Gold(I) cyanide
99.9% trace metals basis
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About This Item
Linear Formula:
AuCN
CAS Number:
Molecular Weight:
222.98
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352300
EC Number:
208-049-1
MDL number:
InChI key
DRJJJWGHLJZDGQ-UHFFFAOYSA-N
InChI
1S/CN.Au/c1-2;
SMILES string
[Au]C#N
assay
99.9% trace metals basis
form
powder
reaction suitability
core: gold
density
7.14 g/mL at 25 °C (lit.)
Quality Level
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1
supp_hazards
Storage Class
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
监管及禁止进口产品
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M W Whitehouse et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 45(12), 579-582 (1996-12-01)
It is suggested that some drugs may be converted by inflammatory cells to yield active species. The transformation may be non-enzymatic, although being driven by the enzymatic production of highly reactive species which are normal products of activated leukocytes, such
Philip M Yangyuoru et al.
Journal of inorganic biochemistry, 102(3), 584-593 (2008-02-08)
The reduction of auricyanide ([Au(CN)(4)](-), a potential gold(III) metabolite of antiarthritic gold(I) compounds), by glutathione (G(-)SH, an anionic biological reductant) proceeds through two intermediates (I(230) and I(290)) which have previously been identified by their UV-vis spectra, but not isolated. Negative-ion
G G Graham et al.
Inflammopharmacology, 16(3), 126-132 (2008-06-04)
The aurocyanide anion, Au(CN) (2) (-) , is a human metabolite of several anti-rheumatic gold complexes containing monovalent gold (I) bound to a sulphur ligand. This article reviews some of the chemical and pharmacological properties of this intriguing metabolite, and
Mohammad Fatehi et al.
Biophysical journal, 92(4), 1241-1253 (2006-12-05)
Single channel and macroscopic current recording was used to investigate block of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel pore by the permeant anion Au(CN)2(-). Block was 1-2 orders of magnitude stronger when Au(CN)2(-) was added to the
Philip M Yangyuoru et al.
Journal of inorganic biochemistry, 102(3), 576-583 (2008-02-08)
Electrospray ionization spectra of potential cyanide-containing gold-drug metabolites revealed additional, weak, unanticipated peaks at approximately twice the mass of the gold(I) and gold(III) cyanide complexes. The exact masses correspond to proton-linked bimetallic complexes, [H[Au(CN)(m)](2)](-), (m=2,4). Further investigation revealed a total
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