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Merck
CN

257788

Centrophenoxine hydrochloride

99%

Synonym(s):

(4-Chlorophenoxy)acetic acid 2-(dimethylamino)ethyl ester hydrochloride, 2-(Dimethylamino)ethyl 4-chlorophenoxyacetate hydrochloride, Meclofenoxate hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16ClNO3 · HCl
CAS Number:
3685-84-5
Molecular Weight:
294.17
UNSPSC Code:
12352101
PubChem Substance ID:
329752824
EC Number:
222-975-3
MDL number:
MFCD00012533

Key Documents

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InChI key

FIVHOHCAXWQPGC-UHFFFAOYSA-N

InChI

1S/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H

SMILES string

Cl.CN(C)CCOC(=O)COc1ccc(Cl)cc1

assay

99%

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
13707JN

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R M Salimov et al.
Eksperimental'naia i klinicheskaia farmakologiia, 71(3), 3-5 (2008-07-26)
We have studied the effects of nicotine (0.125, 0.25, and 0.5 mg/kg) and mecamylamine (0.5, 1.5, and 3 mg/kg) in comparison to reference cognition-enhancing drugs piracetam (100 and 300 mg/kg) and meclofenoxate (20, 50, and 100 mg/kg) administered to male
B A Badyshtov et al.
Eksperimental'naia i klinicheskaia farmakologiia, 58(5), 68-71 (1995-09-01)
The study of thermoprotective properties of acephen (300 mg, single dosage) showed an increase (compared to that of placebo) in the maximum endurable time under thermal loading in healthy volunteers: optimization of evaporative heat exchange regime; reduction of the final
Bimla Nehru et al.
Molecular and cellular biochemistry, 290(1-2), 33-42 (2006-09-14)
Potential use of various nootropic drugs have been a burning area of research on account of various physical and chemical insult in brain under different toxicological conditions. One of the nootropic drug centrophenoxine, also known as an anti-aging drug has
S V Krapivin et al.
Vestnik Rossiiskoi akademii meditsinskikh nauk, (6)(6), 7-16 (1995-01-01)
Amphetamine, caffeine, sydnocarb, meclofenoxate, adapromine, midantan, and nomifensine were studied for their effects on bioelectrical activity and Fourier EEG power spectra of the sensomotor cortex, dorsal hippocamp and lateral hypothalamus of freely behaving awake rats. The drop in the absolute
G I Kovalev et al.
Eksperimental'naia i klinicheskaia farmakologiia, 71(1), 12-17 (2008-03-28)
A population of outbred mice of the ICR strain was divided into two subpopulations according to their high (EH mice) or low (EL mice) exploratory efficacy in the closed cross maze test. In addition, the EH and EL mice differed
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