25970
3-Chlorophenylhydrazine hydrochloride
≥97.0% (AT)
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About This Item
Linear Formula:
ClC6H4NHNH2 · HCl
CAS Number:
Molecular Weight:
179.05
EC Number:
219-005-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3565828
MDL number:
InChI key
CRRIAWUJYMLJOE-UHFFFAOYSA-N
InChI
1S/C6H7ClN2.ClH/c7-5-2-1-3-6(4-5)9-8;/h1-4,9H,8H2;1H
SMILES string
Cl[H].NNc1cccc(Cl)c1
assay
≥97.0% (AT)
form
solid
mp
240-245 °C (dec.) (lit.)
Application
3-Chlorophenylhydrazine hydrochloride has been used in the preparation of:
- 1-(3-chlorophenyl)-3,5-diphenyl-1H-pyrazolo[4,3-c]quinolin-4(5H)-one
- 11-(3-chlorophenyl)-9-phenyl-5,6-dihydro-4H,11H-benzo[i,j]- pyrazolo[3,4-b]quinolizin-8-one
- 1-(3-chlorophenyl)-3-(cyclohexyl)-5-(4-phenoxy phenyl)pyrazole
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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Ring closure reactions of 3-arylhydrazonoalkyl-quinolin-2-ones to 1-aryl-pyrazolo [4, 3-c] quinolin-2-ones.
Stadlbauer W and Hojas G.
Journal of Heterocyclic Chemistry, 41(5), 681-690 (2004)
Akihiko Tanitame et al.
Bioorganic & medicinal chemistry, 12(21), 5515-5524 (2004-10-07)
The 4-piperidyl moiety and the pyrazole ring in 1-(3-chlorophenyl)-5-(4-phenoxyphenyl)-3-(4-piperidyl)pyrazole 2, which has previously shown improved DNA gyrase inhibition and target-related antibacterial activity, were transformed to other groups and the in vitro antibacterial activity of the synthesized compounds was evaluated. The
Amina Othmani et al.
Environmental science and pollution research international, 26(25), 25969-25984 (2019-07-06)
This paper suggests a new alternative for the acceleration of dye removal by adopting alternating current instead of direct current in the treatment of methylene blue solutions and industrials effluents, using anodic oxidation on Pb/PbO2 and stainless steel (SS)/PbO2 anodes.
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