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Merck
CN

261947

1,4-Bis(diphenylphosphino)butane

98%, solid

Synonym(s):

1,4-Butanediylbis[diphenylphosphine], 1,4-Butylenebis(diphenylphosphine), Tetramethylenebis(diphenylphosphine), dppb

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About This Item

Linear Formula:
(C6H5)2P(CH2)4P(C6H5)2
CAS Number:
7688-25-7
Molecular Weight:
426.47
NACRES:
NA.22
PubChem Substance ID:
24855845
UNSPSC Code:
12352002
EC Number:
231-698-7
MDL number:
MFCD00003051
Beilstein/REAXYS Number:
706446

Key Documents

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Product Name

1,4-Bis(diphenylphosphino)butane, 98%

InChI key

BCJVBDBJSMFBRW-UHFFFAOYSA-N

InChI

1S/C28H28P2/c1-5-15-25(16-6-1)29(26-17-7-2-8-18-26)23-13-14-24-30(27-19-9-3-10-20-27)28-21-11-4-12-22-28/h1-12,15-22H,13-14,23-24H2

SMILES string

C(CCP(c1ccccc1)c2ccccc2)CP(c3ccccc3)c4ccccc4

assay

98%

form

solid

reaction suitability

reagent type: ligand
reaction type: Alkylations, reagent type: ligand
reaction type: Heck Reaction, reagent type: ligand
reaction type: Isomerizations, reagent type: ligand
reaction type: Negishi Coupling, reagent type: ligand
reaction type: Sonogashira Coupling, reagent type: ligand
reaction type: Stille Coupling, reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

mp

132-136 °C (lit.)

functional group

phosphine

Quality Level

100

Related Categories

Application

Employed as a ligand in Pd(0)-catalyzed acylcyanation of arylacetylenes and deprotection of allyloxycarbamates.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ9330
MKCV8441
MKCS2286
MKCN7246
MKCL7072

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Trost, B. M.; Schmidt, T.
Journal of the American Chemical Society, 110, 2301-2301 (1988)
Denise Lovison et al.
Dalton transactions (Cambridge, England : 2003), 49(24), 8375-8388 (2020-06-11)
The cationic acetate ruthenium complex [Ru(η1-OAc)(CO)(dppb)(phen)]OAc (1) is easily prepared in 83% yield from [Ru(η1-OAc)(η2-OAc)(CO)(dppb)] (dppb = 1,4-bis(diphenylphosphino)butane) and 1,10-phenanthroline (phen) in MeOH. The derivative 1 undergoes easy substitution of the coordinated acetate by reaction with NaOPiv, KSAc, and KSCN
Steven Giboulot et al.
Dalton transactions (Cambridge, England : 2003), 48(33), 12560-12576 (2019-08-02)
Monocarbonyl complexes [RuCl2(CO)(PR3)(NN)] (R = Cy, NN = en 1, ampy 2; R = iPr; NN = en 3) have been prepared in a one pot reaction from [RuCl2(CO)(dmf)(PPh3)2], PR3 and the NN ligand in CH2Cl2. Treatment of [Ru(OAc)2(CO)(PPh3)2] with
Celisnolia M Leite et al.
Anti-cancer agents in medicinal chemistry, 21(9), 1172-1182 (2020-08-26)
Breast cancer is one of the most common types among women. Its incidence progressively increases with age, especially after age 50. Platinum compounds are not efficient in the treatment of breast cancer, highlighting the use of other metals for the
Lin, I. J. B.; Alper, H.
Journal of the Chemical Society. Chemical Communications, 248-248 (1989)
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