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1-Aminoethylphosphonic acid

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Empirical Formula (Hill Notation):

C₂H₈NO₃P

CAS Number:

Molecular Weight:

125.06

MDL number:

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assay

96%

SMILES string

CC(N)P(O)(O)=O

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New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.

Renata Grzywa et al.

Bioorganic & medicinal chemistry, 18(8), 2930-2936 (2010-03-30)

A series of new aromatic monoesters of alpha-aminoaralkylphosphonic acids were synthesized by selective hydrolysis of corresponding aromatic diesters of alpha-aminoaralkylphosphonic acids. New potential inhibitors of aminopeptidase N/CD13, an enzyme important in tumour angiogenesis, were developed. Some derivatives of the homophenylalanine