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Merck
CN

268895

1-Methoxy-2-propanol

98%

Synonym(s):

Propylene glycol methyl ether, Propyleneglycol monomethyl ether

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About This Item

Linear Formula:
CH3CH(OH)CH2OCH3
CAS Number:
Molecular Weight:
90.12
UNSPSC Code:
12352103
EC Number:
203-539-1
PubChem Substance ID:
Beilstein/REAXYS Number:
1731270
MDL number:
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InChI key

ARXJGSRGQADJSQ-UHFFFAOYSA-N

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

SMILES string

CC(O)COC

vapor density

3.12 (vs air)

vapor pressure

10.9 mmHg ( 25 °C)

assay

98%

autoignition temp.

532 °F

expl. lim.

13.8 %

bp

118-119 °C

density

0.916 g/mL at 25 °C (lit.)

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pictograms

FlameExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

target_organs

Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

93.2 °F - closed cup

flash_point_c

34 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
J Y Domoradzki et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 31-39 (2003-07-15)
The kinetic equivalency of propylene glycol monomethyl ether (PGME), derived from propylene glycol monomethyl ether acetate (PGMEA), as well as the parent compound (PGME) following intravenous administration to Fischer 344 rats was evaluated. In addition, in vitro hydrolysis rates of
Nancy B Hopf et al.
Toxicology letters, 211(1), 77-84 (2012-03-17)
Aging adults represent the fastest growing population segment in many countries. Physiological and metabolic changes in the aging process may alter how aging adults biologically respond to pollutants. In a controlled human toxicokinetic study (exposure chamber; 12 m³), aging volunteers
R A Corley et al.
Toxicology letters, 156(1), 193-213 (2005-02-12)
Propylene glycol monomethyl ether (PM), along with its acetate, is the most widely used of the propylene glycol ether family of solvents. The most common toxic effects of PM observed in animal studies include sedation, very slight alpha(2u)-globulin mediated nephropathy
A Muttray et al.
Toxicology letters, 220(2), 187-192 (2013-04-30)
The German MAK value of 1-methoxypropanol-2 has been fixed at 100 ppm. The aim of this study was to evaluate possible acute effects of an exposure to 100 ppm 1-methoxypropanol-2 on the upper airways of human subjects. Twenty subjects were

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