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Merck
CN

270873

2-Hydroxyquinoline

98%

Synonym(s):

2-Quinolinol, Carbostyril

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
Molecular Weight:
145.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-420-6
MDL number:
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Product Name

2-Hydroxyquinoline, 98%

InChI key

LISFMEBWQUVKPJ-UHFFFAOYSA-N

InChI

1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

SMILES string

Oc1ccc2ccccc2n1

assay

98%

form

crystals

mp

198-199 °C (lit.)

solubility

alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
dilute HCl: soluble(lit.)
water: slightly soluble (1 g/950mL)(lit.)

Quality Level

Application

2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity.

General description

2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1).

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Kamya Bhatnagar et al.
PloS one, 14(11), e0224650-e0224650 (2019-11-07)
The evolution of antibiotic resistance is influenced by a variety of factors, including the availability of resistance mutations, and the pleiotropic effects of such mutations. Here, we isolate and characterize chromosomal quinolone resistance mutations in E. coli, in order to
Edyta Stec et al.
Chembiochem : a European journal of chemical biology, 12(11), 1724-1730 (2011-06-15)
Aurachins are quinoline alkaloids isolated from the myxobacterium Stigmatella aurantiaca. They are substituted with an isoprenoid side chain and act as potent inhibitors in the electron transport chain. A biosynthetic gene cluster that contains at least five genes (auaA-auaE) has
Juan Peris-Vicente et al.
Antibiotics (Basel, Switzerland), 8(4) (2019-11-17)
A method based on micellar liquid chromatography was developed to determine oxolinic acid, ciprofloxacin, enrofloxacin, and sarafloxacin in eggs and egg products. The antimicrobial drugs were obtained in a micellar solution which was directly injected. The analytes were resolved using
Shailesh Kumar Patidar et al.
Biotechnology for biofuels, 11, 102-102 (2018-04-11)
Amelioration of biofuel feedstock of microalgae using sustainable means through synthetic ecology is a promising strategy. The co-cultivation model (Tetraselmis striata and Pelagibaca bermudensis) was evaluated for the robust biofuel production under varying stressors as well as with the selected
Elizabeth M Wagner et al.
Angiogenesis, 18(1), 1-11 (2014-08-26)
Expanded and aberrant bronchial vascularity, a prominent feature of the chronic asthmatic airway, might explain persistent airway wall edema and sustained leukocyte recruitment. Since it is well established that there are causal relationships between exposure to house dust mite (HDM)

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