275778
Imidazo[1,2-a]pyridine
99%
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About This Item
Empirical Formula (Hill Notation):
C7H6N2
CAS Number:
Molecular Weight:
118.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
99%
Form:
liquid
Quality Level
assay
99%
form
liquid
refractive index
n20/D 1.626 (lit.)
bp
103 °C/1 mmHg (lit.)
density
1.165 g/mL at 25 °C (lit.)
SMILES string
c1ccn2ccnc2c1
InChI
1S/C7H6N2/c1-2-5-9-6-4-8-7(9)3-1/h1-6H
InChI key
UTCSSFWDNNEEBH-UHFFFAOYSA-N
General description
In vivo anti-trypanosomal activity of imidazo[1,2-a]pyridiness in the STIB900 mouse model has been investigated.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Martina Hieke et al.
Bioorganic & medicinal chemistry letters, 22(5), 1969-1975 (2012-02-14)
A novel class of 5-lipoxygenase (5-LO) inhibitors characterized by a central imidazo[1,2-a]pyridine scaffold, a cyclohexyl moiety and an aromatic system, is presented. This scaffold was identified in a virtual screening study and exhibits promising inhibitory potential on the 5-LO. Here
Yoshito Terao et al.
Bioorganic & medicinal chemistry letters, 22(24), 7326-7329 (2012-11-14)
Imidazo[1,2-a]pyridine derivatives were designed, synthesized, and evaluated as inhibitors of the apoptosis signal-regulating kinase 1 (ASK1). These were based on a benzothiazole derivative that was discovered from high-throughput screening of our compound library. As a result, we identified potent, selective
Sophie Marhadour et al.
European journal of medicinal chemistry, 58, 543-556 (2012-11-21)
A novel series of 2,3-diarylimidazo[1,2-a]pyridines was synthesized and evaluated for their antileishmanial activities. Four derivatives exhibited good activity against the promastigote and intracellular amastigote stages of Leishmania major, coupled with a low cytotoxicity against the HeLa human cell line. The
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 275778-25G | 04061826169254 |
| 275778-5G | 04061826169285 |