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Merck
CN

282413

2,3-Dimercapto-1-propanol tributyrate

97%

Synonym(s):

BAL tributyrate

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About This Item

Linear Formula:
CH3CH2CH2CO2CH2CH(SCOCH2CH2CH3)CH2SCOCH2CH2CH3
CAS Number:
Molecular Weight:
334.49
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
Form:
liquid
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assay

97%

form

liquid

refractive index

n20/D 1.495 (lit.)

bp

156-160 °C/0.15 mmHg (lit.)

density

1.083 g/mL at 25 °C (lit.)

functional group

ester, thioester

SMILES string

CCCC(=O)OCC(CSC(=O)CCC)SC(=O)CCC

InChI

1S/C15H26O4S2/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3

InChI key

NHBKXEKEPDILRR-UHFFFAOYSA-N

Application

2,3-Dimercapto-1-propanol tributyrate is a thioester analog of triacylglycerol and has been used:
  • in lipase inhibition assay during in vitro screening of medicinal plants as antidiabetics with glucosidase and lipase inhibitory activities
  • in colorimetric microplate assay for lipase activity
  • to analyze positional specificity of LipG (lipase-encoding gene) toward triacylglycerol by a simple continuous spectrophotometric method


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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S Lombard et al.
The Biochemical journal, 358(Pt 3), 773-781 (2001-09-06)
The present study was carried out with a view of determining ricin lipolytic activity on neutral lipids in emulsion and in a membrane-like model. Using 2,3-dimercapto-1-propanol tributyrate (BAL-TC(4)) as substrate, the lipolytic activity of ricin was found to be proportional
[A new simplified colorimetric assay of colipase in duodenal juice using BALB as substrate and its clinical application].
Y Furukawa et al.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 83(7), 1367-1375 (1986-07-01)
Mi-Hwa Lee et al.
Applied and environmental microbiology, 72(11), 7406-7409 (2006-09-05)
We cloned lipG, which encoded a lipolytic enzyme, from a Korean tidal flat metagenomic library. LipG was related to six putative lipases previously identified only in bacterial genome sequences. These enzymes comprise a new family. We partially characterized LipG, providing



Global Trade Item Number

SKUGTIN
282413-1G04061837865251