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Merck
CN

286168

2-Hydroxyestradiol

95%

Synonym(s):

1,3,5(10)-Estratriene-2,3-17β-triol, Estra-1,3,5(10)-triene-2,3,17-triol, NSC 61711

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About This Item

Empirical Formula (Hill Notation):
C18H24O3
CAS Number:
Molecular Weight:
288.38
MDL number:
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assay

95%

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)c(O)cc34)[C@@H]1CC[C@@H]2O

InChI

1S/C18H24O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,17,19-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1

InChI key

DILDHNKDVHLEQB-XSSYPUMDSA-N

Regulatory Information

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Emil Jakobsen et al.
Biochemical pharmacology, 155, 92-101 (2018-06-26)
Soluble adenylate cyclase (sAC) is a non-plasma membrane-bound isoform of the adenylate cyclases signaling via the canonical second messenger, 3',5'-cyclic AMP (cAMP). sAC is involved in key physiological processes such as insulin release, sperm motility, and energy metabolism. Thus, sAC

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