286214
16α-Hydroxyprogesterone
97%
Synonym(s):
16α-Hydroxy-4-pregnene-3,20-dione, 16α-Hydroxypregn-4-ene-3,20-dione, 4-Pregnen-16α-ol-3,20-dione
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About This Item
Empirical Formula (Hill Notation):
C21H30O3
CAS Number:
Molecular Weight:
330.46
UNSPSC Code:
12352103
MDL number:
SMILES string
CC(=O)[C@H]1[C@H](O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
assay
97%
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E Vanluchene et al.
Journal of steroid biochemistry, 35(1), 83-89 (1990-01-01)
A method is presented based on capillary GLC using both a thermionic and a flame ionization detector to simultaneously analyse all major unconjugated steroids in ovarian follicular fluids (FF). Although specificity can not always be guaranteed for the smaller concentrations
V D Bokkenheuser et al.
Journal of lipid research, 22(1), 95-102 (1981-01-01)
16 alpha-Hydroxyprogesterone, precursor of biliary 16 alpha-hydroxypregnanolone, was incubated with mixed fecal flora of humans and rats. The major steroid metabolite formed in both systems was 3 alpha-hydroxy-17 alpha-pregnan-20-one. These results demonstrated that the fecal flora reduced the delta 4-3
A Yamada et al.
The Journal of biological chemistry, 276(7), 4604-4610 (2000-09-21)
It is well known that several 3-keto-4-ene steroids such as progesterone and testosterone are metabolized in a gender-specific or -predominant manner by adult rat liver microsomes. In the male, these steroids are primarily metabolized into two oxidized (16alpha-hydroxyl and 6beta-hydroxyl)
J E Buster et al.
The Journal of clinical endocrinology and metabolism, 46(6), 907-910 (1978-06-01)
Seven plasma samples from five normal third trimester pregnant women, drawn every 5 and 15 min at similar times on 2 days, 2 days apart, were measured in quadruplicate for estradiol (E2), estriol, progesterone, 16 alpha-hydroxyprogesterone, and 17 alpha-hydroxyprogesterone (17P).
H Inano et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 81(1), 55-57 (1985-01-01)
Radioactive 16 alpha-hydroxyprogesterone was obtained as one of the major metabolites of [14C]pregnenolone and progesterone by testicular homogenates of an adult crab-eating monkey (Macaca irus). 16 alpha-hydroxylation of progesterone occurred by incubation of testes of men and and the monkey
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