286567
Mephenesin
98%
Synonym(s):
3-(2-Methylphenoxy)-1,2-propanediol
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About This Item
Linear Formula:
CH3C6H4OCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
182.22
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.25
Assay
98%
form
powder
bp
153-154 °C/4 mmHg (lit.)
mp
69-71 °C (lit.)
SMILES string
Cc1ccccc1OCC(O)CO
InChI
1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3
InChI key
JWDYCNIAQWPBHD-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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S Bertrand et al.
The European journal of neuroscience, 11(2), 583-592 (1999-03-03)
The in vitro newborn rat isolated brain stem/spinal cord preparation was used to study the involvement of presynaptic inhibition in the control of the synaptic locomotor drive. The recording chamber was partitioned with Vaseline walls to separate the L1-L2 locomotor
C Bachmeyer et al.
Annales de dermatologie et de venereologie, 123(3), 185-187 (1996-01-01)
Mephenesin is a muscle relaxant, mostly applied locally in trauma. It is a component of Traumalgyl cream in association with phenylbutazone. Contact dermatitis due to mephenesin is exceptional. We report here a case of a woman who developed after application
Shohei Yamamoto et al.
Brain research, 1082(1), 115-123 (2006-03-02)
Nociceptive signals are transmitted to the spinal dorsal horn via primary afferent fibers, and the signals induce withdrawal reflexes by activating spinal motoneurons in the ventral horn. Therefore, nociceptive stimuli increase motoneuronal firing and ventral root discharges. This study was
B Nickel et al.
Arzneimittel-Forschung, 40(8), 909-911 (1990-08-01)
The influence of the skeletal muscle tone by flupirtine (D-9998, Katadolon; CAS 56995-20-1), some selected analgesics and muscle relaxants was investigated in conscious rats after intraperitoneal administration. Benzodiazepines (diazepam and tetrazepam), baclofen, dantrolene and mephenesine reduced the tone of the
Laurent Fanton et al.
Journal of forensic sciences, 52(1), 221-223 (2007-01-11)
This report describes a death related to the abuse of and intoxication by mephenesin. To the best of our knowledge, this is the first report case of lethal intoxication involving solely mephenesin and reporting mephenesin blood concentrations. The victim was
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