287571
Bis(2,2,2-trifluoroethyl) ether
98%
Synonym(s):
2,2,2-Trifluoroethyl ether, Flurothyl
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About This Item
Linear Formula:
(CF3CH2)2O
CAS Number:
Molecular Weight:
182.06
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1811927
Assay:
98%
Form:
liquid
InChI
1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2
SMILES string
FC(F)(F)COCC(F)(F)F
InChI key
KGPPDNUWZNWPSI-UHFFFAOYSA-N
assay
98%
form
liquid
Quality Level
bp
62-63 °C (lit.)
density
1.404 g/mL at 25 °C (lit.)
functional group
ether, fluoro
Related Categories
Application
Bis(2,2,2-trifluoroethyl) ether was used to diminish self-discharge of Li-S cells having both low- and high-sulfur-loading sulfur cathodes.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
33.8 °F - closed cup
flash_point_c
1 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves
Regulatory Information
危险化学品
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Stacey B B Dutton et al.
Epilepsia, 52(11), 2050-2056 (2011-08-02)
We evaluated the ability of the ketogenic diet (KD) to improve thresholds to flurothyl-induced seizures in two mouse lines with Scn1a mutations: one that models Dravet syndrome (DS) and another that models genetic (generalized) epilepsy with febrile seizures plus (GEFS+).
Marcella M Lucas et al.
Brain : a journal of neurology, 134(Pt 6), 1684-1693 (2011-05-24)
One of the most common and serious co-morbidities in patients with epilepsy is cognitive impairment. While early-life seizures are considered a major cause for cognitive impairment, it is not known whether it is the seizures, the underlying neurological substrate or
Li-Li Li et al.
Frontiers in neurology, 9, 802-802 (2018-10-16)
The role of leptin in the pathogenesis of epilepsy is getting more and more attention in clinical and basic research. Although there are data indicating neuroprotective effects of elevated serum/brain leptin levels following acute seizures, no study to date has
Yogendrasinh H Raol et al.
Annals of neurology, 65(3), 326-336 (2009-04-01)
Neonatal seizures occur frequently, are often refractory to anticonvulsants, and are associated with considerable morbidity and mortality. Genetic and electrophysiological evidence indicates that KCNQ voltage-gated potassium channels are critical regulators of neonatal brain excitability. This study tests the hypothesis that
David N Ruskin et al.
PloS one, 8(6), e65021-e65021 (2013-06-12)
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and communication deficits. Incidence is rising, and current treatments are inadequate. Seizures are a common comorbidity, and since the 1920's a high-fat, low-carbohydrate ketogenic diet has been used to
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