291277
Undecanoic δ-lactone
98%
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About This Item
Empirical Formula (Hill Notation):
C11H20O2
CAS Number:
Molecular Weight:
184.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
211-915-1
MDL number:
Assay:
98%
InChI key
YZRXRLLRSPQHDK-UHFFFAOYSA-N
InChI
1S/C11H20O2/c1-2-3-4-5-7-10-8-6-9-11(12)13-10/h10H,2-9H2,1H3
SMILES string
CCCCCCC1CCCC(=O)O1
assay
98%
Gene Information
human ... CYP1A2(1544)
bp
152-155 °C/10.5 mmHg (lit.)
density
0.969 g/mL at 25 °C (lit.)
functional group
ester
General description
Undecanoic δ-lactone has been found to be best substarte for good substrates for lactonase from Sulfolobus islandicus (SisLac).
Application
Undecanoic δ-lactone has been used as substrate to investigate the activities of stimulated and nonstimulated human serum paraoxonase (PON1) samples.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
312.8 °F
flash_point_c
156 °C
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
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S Billecke et al.
Drug metabolism and disposition: the biological fate of chemicals, 28(11), 1335-1342 (2000-10-19)
It is well established that human serum paraoxonase (PON1) catalyzes the hydrolysis of organophosphate insecticides and nerve agents, as well as that of a number of aromatic carboxylic acid esters. Our laboratory has recently found a new class of PON1
Julien Hiblot et al.
PloS one, 7(10), e47028-e47028 (2012-10-17)
A new member of the Phosphotriesterase-Like Lactonases (PLL) family from the hyperthermophilic archeon Sulfolobus islandicus (SisLac) has been characterized. SisLac is a native lactonase that exhibits a high promiscuous phosphotriesterase activity. SisLac thus represents a promising target for engineering studies
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