293369
3-Aminopiperidine dihydrochloride
97%
Synonym(s):
3-Piperidinamine dihydrochloride
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About This Item
Empirical Formula (Hill Notation):
C5H12N2 · 2HCl
Molecular Weight:
173.08
UNSPSC Code:
12352100
PubChem Substance ID:
MDL number:
Assay:
97%
Form:
solid
InChI
1S/C5H12N2.2ClH/c6-5-2-1-3-7-4-5;;/h5,7H,1-4,6H2;2*1H
SMILES string
Cl.Cl.NC1CCCNC1
InChI key
GGPNYXIOFZLNKW-UHFFFAOYSA-N
assay
97%
form
solid
mp
230 °C (dec.) (lit.)
General description
Estimation of (S)-piperidin-3-amine in (R)-piperidin-3-amine dihydrochloride (3-aminopiperidine dihydrochloride) has been investigated by chiral high-performance liquid chromatographic (chiral HPLC) method.
Application
Reactant for N-arylation of heterocyclic diamines
Reactant for synthesis of substituted quinolones with reduced phototoxic risk
Reactant for synthesis of substituted quinolones with reduced phototoxic risk
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Shubo Dong et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 33(3), 293-298 (2017-03-18)
A sensitive non-derivatization method for the determination of the highly polar compound 3-aminopiperidine was developed using a mixed-mode column combined with a charged aerosol detector (CAD). Chromatographic conditions, including the type of detector, separation mode, and mobile phase composition, were
Chittabathina Venkata Raghunadha Babu et al.
Chirality, 26(12), 775-779 (2014-07-22)
A simple, precise, accurate, robust chiral high-performance liquid chromatographic (chiral HPLC) method was developed for estimation of (S)-piperidin-3-amine (S-isomer) in (R)-piperidin-3-amine dihydrochloride (R-AMP). As AMP is a high-melting solid and nonchromophoric compound, development of a suitable chiral method is a
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