293407
2-Quinoxalinecarboxylic acid
97%
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About This Item
Empirical Formula (Hill Notation):
C9H6N2O2
CAS Number:
Molecular Weight:
174.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
InChI
1S/C9H6N2O2/c12-9(13)8-5-10-6-3-1-2-4-7(6)11-8/h1-5H,(H,12,13)
SMILES string
OC(=O)c1cnc2ccccc2n1
InChI key
UPUZGXILYFKSGE-UHFFFAOYSA-N
assay
97%
mp
208 °C (dec.) (lit.)
functional group
carboxylic acid
Quality Level
General description
Linear and Freundlich adsorption isotherm coefficient of 2-quinoxalinecarboxylic acid has been evaluated.
Application
2-Quinoxalinecarboxylic acid has been used in the preparation of:
- N-(2-quinoxaloyl)-α-amino acids
- bisquinoxaloyl (bisquinoxalinecarbonyl) derivatives
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Alex P Praseuth et al.
Biotechnology progress, 24(1), 134-139 (2008-01-05)
Proficient production of the antitumor agent triostin A was developed using engineered Escherichia coli (E. coli). The bacterium played host to 15 genes that encode integral biosynthetic proteins which were identified and cloned from Streptomyces lasaliensis. In this study, triostin
Kento Koketsu et al.
Organic letters, 8(21), 4719-4722 (2006-10-06)
[reaction: see text] Little is known about how quinoxaline-2-carboxylic acid (QC) is synthesized in nature. On the basis of analysis of echinomycin biosynthetic gene clusters as well as feeding experiments with labeled precursors, we have proposed a biosynthetic pathway to
Synthetic Approaches to Quinoxaline Antibiotics. Synthesis of Bisquinoxaloyl Derivatives1a.
Koppel HC, et al.
The Journal of Organic Chemistry, 28(4), 1119-1122 (1963)
M Rutalj et al.
Food additives and contaminants, 13(8), 879-882 (1996-11-01)
The concentration of quinoxaline-2-carboxylic acid (QCA) determined by HPLC after alkaline hydrolysis of liver and muscle of swine, ranged from < 3 ng/g to 45.3 ng/g in liver, and from < 3 ng/g to 10.8 ng/g in muscle samples. After
Lingli Huang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 874(1-2), 7-14 (2008-10-08)
Cyadox (CYX) is an antimicrobial growth-promoter of the quinoxalines. It is highly effective on improving growth and feed conversion of chicken with little toxicity. For food safety concerns, HPLC-UV methods were developed for the sequential determination of CYX and its
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