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Merck
CN

293490

2-Benzylimidazoline

99%

Synonym(s):

2-Benzyl-2-imidazoline, 2-Benzyl-4,5-dihydro-1H-imidazole, Benzidazol, NSC 35110, Phenylmethylimidazoline, Tolazoline

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About This Item

Empirical Formula (Hill Notation):
C10H12N2
CAS Number:
Molecular Weight:
160.22
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-448-9
MDL number:
Assay:
99%
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InChI key

JIVZKJJQOZQXQB-UHFFFAOYSA-N

InChI

1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12)

SMILES string

C1CN=C(Cc2ccccc2)N1

assay

99%

mp

66-69 °C (lit.)

solubility

alcohol: freely soluble, chloroform: soluble, diethyl ether: very slightly soluble, ethyl acetate: very slightly soluble, water: freely soluble

functional group

phenyl

storage temp.

2-8°C

Application

2-Benzylimidazoline has been used in the preparation of phenyl-2,3-dihydroimidazo[1,2-a]pyridinone derivatives via condensation with of a series of β-keto esters.
Reactant for synthesis of imidazoline-containing drug

General description

2-Benzylimidazoline is an active vasodilator.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Onder Teskin et al.
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The radial artery is increasingly being used in coronary revascularization as an alternative conduit to a saphenous vein graft. Its perfect endothelial capacity provides a high patency rate comparable with the internal mammary artery (IMA). However, its spastic characteristics cause
An improved procedure for preparing 2-(2-hetaryl) imidazolines and their analogs.
Aleksandrov AA and El'chaninov MM.
Russian Journal of Applied Chemistry, 82(12), 2161-2165 (2009)
Brad F Miller et al.
Journal of wildlife diseases, 40(3), 533-537 (2004-10-07)
A combination of tiletamine-zolazepam/xylazine (TZ/X) is effective in the chemical immobilization of white-tailed deer (Odocoileus virginianus); however, the lengthy duration of immobilization may limit its usefulness. From October to November 2002, 21 captive female deer were assigned randomly to an
Tulio M Prado et al.
Veterinary anaesthesia and analgesia, 35(3), 201-207 (2008-02-20)
To evaluate the anesthetic and cardiorespiratory effects of two doses of intramuscular (IM) xylazine/ketamine in alpacas, and to determine if tolazoline would reduce the anesthetic recovery time. Prospective randomized crossover study. Six castrated male alpacas. Each alpaca received a low
J A E Hubbell et al.
Equine veterinary journal, 38(3), 238-241 (2006-05-19)
The ability to shorten the duration of sedation would potentially improve safety and utility of detomidine. To determine the effects of tolazoline and atipamezole after detomidine sedation. Administration of tolazoline or atipamezole would not affect detomidine sedation. In a randomised

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