Key Documents

View All Documentation

300721

Di-tert-butyl nitroxide

Name: Di-<I>tert</I>-butyl nitroxide
Brand: ALDRICH

technical grade, 90%

Select a Size

Change View

About This Item

Linear Formula:

[(CH₃)₃C]₂NO

CAS Number:

2406-25-9

Molecular Weight:

145.24

NACRES:

NA.22

PubChem Substance ID:

24857936

UNSPSC Code:

12352000

EC Number:

219-298-0

MDL number:

MFCD00008800

Assay:

90%

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

grade

technical grade

assay

90%

refractive index

n20/D 1.435 (lit.)

bp

74-75 °C/34 mmHg (lit.)

functional group

amine

storage temp.

2-8°C

SMILES string

CC(C)(C)N([O])C(C)(C)C

InChI

1S/C8H18NO/c1-7(2,3)9(10)8(4,5)6/h1-6H3

InChI key

CKJMHSMEPSUICM-UHFFFAOYSA-N

Description

Application

Di-tert-butyl nitroxide (DTBN) can be used as:

An additive for the synthesis of N-sulfenylimines by oxidative coupling of amines and disulfides or thiols using a copper-based metal-organic framework (MOF) as a catalyst.
An initiator in the controlled radical polymerization reactions.
A reagent in the preparation of N-aroyl-o-aroyl-N-tert-butylhdroxylamines by reacting with aromatic acid chlorides.

Reagent for the room-temperature oxidation of primary and secondary benzylamines to imines and for the ESR study of Lewis acid centers in Zeolite X.

Spin label. Has been used in localization of lipid microdomains and thermal phenomena in murine stratum corneum.

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

114.8 °F - closed cup

flash_point_c

46 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides.

S I Dikalov et al.

The Journal of biological chemistry, 274(14), 9392-9399 (1999-03-27)

Amyloid beta (Abeta) peptides play an important role in the pathogenesis of Alzheimer's disease. Free radical generation by Abeta peptides was suggested to be a key mechanism of their neurotoxicity. Reports that neurotoxic free radicals derived from Abeta-(1-40) and Abeta-(25-35)

Direct synthesis of N-sulfenylimines through oxidative coupling of amines with disulfides/thiols over copper based metal-organic frameworks

Long, W, et al.

Royal Society of Chemistry Advances, 6(47), 40945-40952 (2016)

Molecular dynamics and partitioning of di-tert-butyl nitroxide in stratum corneum membranes: effect of terpenes.

Heverton Silva Camargos et al.

Lipids, 45(5), 419-427 (2010-04-03)

In this work, we have used electron paramagnetic resonance (EPR) spectroscopy of the small spin label di-tert-butyl nitroxide (DTBN), which partitions the aqueous and hydrocarbon phases, to study the interaction of the terpenes alpha-terpineol, 1,8-cineole, L(-)-carvone and (+)-limonene with the

View All Related Papers

Global Trade Item Number

SKU	GTIN
300721-1G	04061838135261