308358
2′,3′-Dideoxycytidine
99%
Synonym(s):
ddC
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About This Item
Empirical Formula (Hill Notation):
C9H13N3O3
CAS Number:
Molecular Weight:
211.22
UNSPSC Code:
12352103
Beilstein/REAXYS Number:
654956
MDL number:
InChI key
WREGKURFCTUGRC-POYBYMJQSA-N
SMILES string
NC1=NC(=O)N(C=C1)[C@H]2CC[C@@H](CO)O2
InChI
1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s1
assay
99%
optical activity
[α]20/D +75°, c = 0.6 in H2O
mp
217-218 °C (lit.)
Application
Research tool for antiviral (e.g. HIV-1) and anticancer studies.
Regulatory Information
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M Smith et al.
Clinical and investigative medicine. Medecine clinique et experimentale, 17(3), 226-243 (1994-06-01)
Nucleoside antagonists of human immunodeficiency virus (HIV) reverse transcriptase (RT) activity have been commonly used in the therapy of HIV-associated disease. The prolonged use of such drugs has led to the development of HIV variants that display resistance against these
Aldrichimica Acta, 20, 52-52 (1987)
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