309346
L-Glutamic acid diethyl ester hydrochloride
97%
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About This Item
Linear Formula:
C2H5OCOCH2CH2CH(NH2)COOC2H5 · HCl
CAS Number:
Molecular Weight:
239.70
Beilstein:
3597595
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
Assay
97%
optical activity
[α]18/D +22°, c = 1 in H2O
reaction suitability
reaction type: solution phase peptide synthesis
mp
108-110 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl[H].CCOC(=O)CC[C@H](N)C(=O)OCC
InChI
1S/C9H17NO4.ClH/c1-3-13-8(11)6-5-7(10)9(12)14-4-2;/h7H,3-6,10H2,1-2H3;1H/t7-;/m0./s1
InChI key
WSEQLMQNPBNMSL-FJXQXJEOSA-N
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Application
L-Glutamic acid diethyl ester hydrochloride can be used in the synthesis of:
- Oligo(γ-ethyl L-glutamate) via oligomerization catalyzed by papain.
- L-glutamic acid based dendritic compounds.
- Poly(α-peptide) by polymerization and copolymerization in the presence of protease catalysts.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Rapid regioselective oligomerization of L-glutamic acid diethyl ester catalyzed by papain
Li G, et al.
Macromolecules, 39(23), 7915-7921 (2006)
K Horie et al.
Life sciences, 57(8), 735-741 (1995-01-01)
Novel vasoconstrictor peptides, endothelin-1 (ET-1) and endothelin-3 (ET-3), are also known as neuropeptides or neuromodulators. When either ET-1 or ET-3 was administered to the rat striatum via a microinjection needle, the dopamine release from the striatum dose-dependently increased. Pretreatment with
F Barnabi et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 281(5), R1665-R1674 (2001-10-20)
Neurotransmitters relaying ascending visceral information were examined by comparing the response of neurons in the insular cortex to vagal stimulation (0.8 Hz, 2 mA) before and after neurotransmitter antagonist injections (200 nl) in the ventroposterior parvocellular nucleus of the thalamus
P D Evans et al.
The Journal of experimental biology, 173, 229-249 (1992-12-01)
L-Glutamate application can produce three different responses in the membrane potential of the Schwann cell of the tropical squid, Sepioteuthis sepioidea, which appear to be mediated by three pharmacologically distinct classes of receptor. A class of non-NMDA-type receptors, with some
Ultrasound induced formation of organogel from a glutamic dendron
Li Y, et al.
Tetrahedron, 63(31), 7468-7473 (2007)
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