Skip to Content
Merck
CN

Key Documents

View All Documentation

309567

(Methoxymethyl)triphenylphosphonium chloride

97%

Synonym(s):

Triphenyl(methoxymethyl)phosphonium chloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
(C6H5)3P(Cl)CH2OCH3
CAS Number:
4009-98-7
Molecular Weight:
342.80
UNSPSC Code:
12352107
NACRES:
NA.22
PubChem Substance ID:
24858739
EC Number:
223-664-5
Beilstein/REAXYS Number:
3599844
MDL number:
MFCD00011800
Assay:
97%
Form:
solid
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

assay

97%

form

solid

reaction suitability

core: phosphonium, reaction type: C-C Bond Formation

mp

185-195 °C (dec.) (lit.)

functional group

ether, phosphine

SMILES string

[Cl-].COC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C20H20OP.ClH/c1-21-17-22(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1

InChI key

SJFNDMHZXCUXSA-UHFFFAOYSA-M

Application

(Methoxymethyl)triphenylphosphonium chloride is a Wittig reagent that reacts with aldehydes and ketones to give substituted alkenes. This Wittig reaction finds application as the key step in the synthesis of:
  • Antimalarial drug, (+)-artemisinin.
  • Substituted quinolines.
  • Akuammiline alkaloid picrinine.
  • 7H-pyrrolo[2,3-d]pyrimidine derivatives for signal transducers and activators of transcription 6 (STAT6) inhibitors.

Still not finding the right product?

Explore all of our products under (Methoxymethyl)triphenylphosphonium chloride

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

>482.0 °F

flash_point_c

> 250 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBJ3983
STBF8796V
STBD1725V
STBB7728V
STBB3862V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Total synthesis of the akuammiline alkaloid picrinine
Smith JM, et al.
Journal of the American Chemical Society, 136(12), 4504-4507 (2014)
Stereoselective total synthesis of (+)-artemisinin
Yadav JS, et al.
Tetrahedron Letters, 44(2), 387-389 (2003)
Novel 7H-pyrrolo [2, 3-d] pyrimidine derivatives as potent and orally active STAT6 inhibitors
Nagashima S, et al.
Bioorganic & Medicinal Chemistry, 17(19), 6926-6936 (2009)
View All Related Papers

Global Trade Item Number

SKUGTIN
309567-25G04061826676097
309567-100G04061826676059