309923
Ethyl nitrite solution
10-20 wt. % in ethanol
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About This Item
Linear Formula:
C2H5ONO
CAS Number:
Molecular Weight:
75.07
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form
liquid
concentration
10-20 wt. % in ethanol
refractive index
n20/D 1.36
density
0.792 g/mL at 25 °C
functional group
O-nitroso
nitroso
storage temp.
2-8°C
SMILES string
CCON=O
InChI
1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3
InChI key
QQZWEECEMNQSTG-UHFFFAOYSA-N
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General description
The reactions of ethyl nitrite solution with human haemoglobin and sperm whale myoglobin were studied.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
59.0 °F - closed cup
Flash Point(C)
15 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
危险化学品
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M P Doyle et al.
The Journal of biological chemistry, 256(23), 12399-12404 (1981-12-10)
The reactions of human hemoglobin and sperm whale myoglobin with ethyl nitrite under aerobic conditions have been examined in kinetic detail. Ethyl nitrite converts two equivalents of oxyhemoglobin or oxymyoglobin to their oxidized counterparts with concurrent production of one equivalent
Alessio Baccarani et al.
Journal of reconstructive microsurgery, 23(5), 257-262 (2007-09-19)
Vasospasm leading to thrombosis is a major cause of free flap failure. Flap blood flow may improve by application of vasodilating agents to the pedicle. The purpose of this study is to evaluate the effect of a novel S-nitrosylating agent
Basil M Yurcisin et al.
Annals of surgery, 257(5), 971-977 (2013-01-31)
To determine if reduction in nitric oxide bioactivity contributes to the physiological instability that occurs after brain death and, if so, to also determine in this setting whether administration of a renitrosylating agent could improve systemic physiological status. Organ function
Martin P Moya et al.
Lancet (London, England), 360(9327), 141-143 (2002-07-20)
Inhaled nitric oxide is used to alleviate pulmonary hypertension and hypoxaemia, but generates toxic free radicals and oxides of nitrogen (NO(x)), which can cause rebound-hypoxia and additional pulmonary and other morbidity. To address these problems, we assessed the efficacy of
Takuma Yoshikawa et al.
International journal of pharmaceutics, 583, 119352-119352 (2020-04-24)
Although monoclonal antibodies (mAbs) have revolutionized cancer treatment, their accumulation in solid tumors is limited and requires improvement to enhance therapeutic efficacy. Here we developed a strategy to modify mAb with a donor of nitric oxide (NO) because NO functions
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