327115
o-Toluidine hydrochloride
98%
Synonym(s):
2-Methylaniline hydrochloride
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About This Item
Linear Formula:
CH3C6H4NH2 · HCl
CAS Number:
Molecular Weight:
143.61
EC Number:
211-252-8
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3558629
MDL number:
Assay:
98%
InChI key
OGVXWEOZQMAAIM-UHFFFAOYSA-N
InChI
1S/C7H9N.ClH/c1-6-4-2-3-5-7(6)8;/h2-5H,8H2,1H3;1H
SMILES string
Cl.Cc1ccccc1N
assay
98%
mp
215-217 °C (lit.)
General description
o-Toluidine hydrochloride is a demonstrated animal carcinogen.
Application
o-Toluidine hydrochloride was used in preparation of 9,9-bis(3-methyl-4-aminophenyl)fluorine.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
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M Elwell
Toxicity report series, 44, 1-C8-1-C8 (2002-07-16)
o-Nitrotoluene and o-toluidine hydrochloride are structurally related chemicals that are suspected and demonstrated animal carcinogens, respectively. The metabolic potential of the gastrointestinal flora is considered an important factor in o-nitrotoluene-induced toxicity and involves the reduction of the nitro group to
Ortho alkyl substituents effect on solubility and thermal properties of fluorenyl cardo polyimides.
Hu Z, et al.
Polymer, 46(14), 5278-5283 (2005)
An o-toluidine method for body-fluid glucose determination.
Kurt M Dubowski
Clinical chemistry, 54(11), 1919-1920 (2008-10-30)
Tania Carreón et al.
Occupational and environmental medicine, 67(5), 348-350 (2009-11-04)
In 1991, the US National Institute for Occupational Safety and Health (NIOSH) reported an increased bladder cancer risk in a cohort of 1749 workers potentially exposed to o-toluidine and aniline at a chemical manufacturing plant. As additional information showed that
Qishu Qu et al.
Se pu = Chinese journal of chromatography, 28(3), 260-263 (2010-06-17)
Bare nonporous silica particles with diameter around 1 microm were prepared. A 20 cm section of a total length of 45 cm capillary (100 microm i. d.) was packed electrokinetically and the separation performance of basic compounds was investigated in
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