327859
2′,3′-Dideoxy-5-iodouridine
97%
Synonym(s):
5-Iodo-2′,3′-dideoxyuridine
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About This Item
Empirical Formula (Hill Notation):
C9H11IN2O4
CAS Number:
Molecular Weight:
338.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5956836
Assay:
97%
InChI
1S/C9H11IN2O4/c10-6-3-12(9(15)11-8(6)14)7-2-1-5(4-13)16-7/h3,5,7,13H,1-2,4H2,(H,11,14,15)/t5-,7+/m0/s1
SMILES string
OC[C@@H]1CC[C@@H](O1)N2C=C(I)C(=O)NC2=O
InChI key
OBGFSDPYSQAECJ-CAHLUQPWSA-N
assay
97%
mp
176 °C (dec.) (lit.)
storage temp.
2-8°C
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General description
2′,3′-Dideoxy-5-iodouridine is commonly used as research tool for antiviral and anticancer studies.
Application
2′,3′-Dideoxy-5-iodouridine (5-Iodo-2′,3′-dideoxyuridine) was used in preparation of fluorescence-tagged chain-terminating reagents, T-526, for rapid DNA sequencing.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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J M Prober et al.
Science (New York, N.Y.), 238(4825), 336-341 (1987-10-16)
A DNA sequencing system based on the use of a novel set of four chain-terminating dideoxynucleotides, each carrying a different chemically tuned succinylfluorescein dye distinguished by its fluorescent emission is described. Avian myeloblastosis virus reverse transcriptase is used in a
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Aldrichimica Acta, 20, 52-52 (1987)
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