Skip to Content
Merck
CN

Key Documents

View All Documentation

346160

Ethynylmagnesium chloride solution

0.5 M in THF

Synonym(s):

Chloromagnesium acetylide

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
CH≡CMgCl
CAS Number:
65032-27-1
Molecular Weight:
84.79
NACRES:
NA.22
PubChem Substance ID:
24861377
UNSPSC Code:
12352103
MDL number:
MFCD00075343
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

liquid

Quality Level

100

reaction suitability

reaction type: Grignard Reaction

packaging

Sure/Seal™ of

concentration

0.5 M in THF

density

0.921 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

Cl[Mg]C#C

InChI

1S/C2H.ClH.Mg/c1-2;;/h1H;1H;/q;;+1/p-1

InChI key

YEWNLGTVYUADOR-UHFFFAOYSA-M

Application

Ethynylmagnesium chloride solution can be used:
  • To synthesize 1-ethynyldeoxyribose derivatives which can further undergo Sonogashira coupling with various aryl, heteroaryl, and metallocenyl derivatives.
  • In one of the key synthetic steps of substituted naphthostyrils.
  • In the preparation of propargylic ester precursor for the synthesis of 1,3-dienylphosphonates.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

EUH019

Storage Class

4.3 - Hazardous materials which set free flammable gases upon contact with water

wgk

WGK 3

flash_point_f

-16.6 °F - closed cup

flash_point_c

-27 °C - closed cup

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBP4388
SHBP3531
SHBN9136
SHBN9135
SHBN3133

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A novel and convenient method for the synthesis of substituted naphthostyrils
Liu J, et al.
Tetrahedron Letters, 44(12), 2545-2548 (2003)
Sonogashira reactions of α-and β-1-ethynyl-2-deoxyribosides: synthesis of acetylene-extended C-nucleosides
Bobula T, et al.
Tetrahedron, 66(2), 530-536 (2010)
New and efficient synthesis of 1, 3-dienylphosphonates by Palladium-catalyzed substitution of propargylic esters to diethyl phosphite
Liu X, et al.
Synthetic Communications, 43(19), 2622-2626 (2013)

Global Trade Item Number

SKUGTIN
346160-100ML04061826761007
346160-800ML04061838135407