346616
1,2-Naphthoquinone
97%
Synonym(s):
β-Naphthoquinone
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About This Item
Empirical Formula (Hill Notation):
C10H6O2
CAS Number:
Molecular Weight:
158.15
EC Number:
208-360-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
606546
MDL number:
Assay:
97%
Form:
powder
assay
97%
form
powder
mp
139-142 °C (dec.) (lit.)
functional group
ketone
SMILES string
O=C1C=Cc2ccccc2C1=O
InChI
1S/C10H6O2/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6H
InChI key
KETQAJRQOHHATG-UHFFFAOYSA-N
Gene Information
human ... PTPRC(5788)
General description
1,2-Naphthoquinone is one of the major metabolite of naphthalene, which is responsible for the cytotoxicity and genotoxicity associated with it. 1,2-Naphthoquinone is an atmospheric contaminant. It causes the contraction of trachea smooth muscles in guinea pig through the activation of epidermal growth factor receptor. 1,2-Naphthoquinone has been reported as an environmental quinone in diesel exhaust particles (DEP) and atmospheric particulate matter.
Application
1,2-Naphthoquinone was employed as mediator during electrochemical mapping of redox activity in normal human breast (MCF-10A) cells by scanning electrochemical microscopy (SECM).
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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