357871
5-Mercapto-1-methyltetrazole
98%
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About This Item
Empirical Formula (Hill Notation):
C2H4N4S
CAS Number:
Molecular Weight:
116.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
98%
form
powder
mp
125-128 °C (lit.)
SMILES string
Cn1nnnc1S
InChI
1S/C2H4N4S/c1-6-2(7)3-4-5-6/h1H3,(H,3,5,7)
InChI key
XOHZHMUQBFJTNH-UHFFFAOYSA-N
General description
5-Mercapto-1-methyltetrazole is a heterocyclic thiol derivative. It forms dimeric or tetrameric complexes with trimethylgallium.
Application
5-Mercapto-1-methyltetrazole may be employed as heterocyclic ligand to study the geometry and stereochemical activity of the lone pair at the lead atom in hemi- and holo-directed lead(II) complexes. It may be used in the chemical modification of submicron particles of mesoporous MSU-2 silica and SBA-15 mesoporous silica.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
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W Peetermans et al.
Acta clinica Belgica, 45(5), 327-333 (1990-01-01)
Treatment with MTT side chain containing cephalosporins can result in a clinically relevant coagulopathy due to a deficiency in active vitamin K dependent clotting factors. This complication is not caused by a decreased production of vitamin K by the intestinal
J J Schentag et al.
American journal of surgery, 155(5A), 40-44 (1988-05-31)
Normal volunteers and patients were studied to determine the relative importance of NMTT and patient risk factors in the production of hypoprothrombinemia. The normal volunteers demonstrated in vivo NMTT production, but the order of magnitude (cefoperazone, moxalactam, and cefotetan in
C S Ingalls et al.
Clinical therapeutics, 11(5), 640-651 (1989-09-01)
The effects of moxalactam and free N-methylthiotetrazole (N-MTT) in vitro on platelet aggregation induced by adenosine diphosphate (ADP), arachidonic acid, collagen, epinephrine, or ristocetin were determined. Moxalactam at concentrations of 1.9 mM and 5.7 mM inhibited platelet aggregation induced by
Damián Pérez-Quintanilla et al.
Journal of colloid and interface science, 313(2), 551-562 (2007-05-29)
A mesoporous silica (MCM-41) has been chemically modified with 5-mercapto-1-methyltetrazole using the homogeneous route. This synthetic route involved the reaction of 5-mercapto-1-methyltetrazole with 3-chloropropyltriethoxysilane prior to immobilization on the support. The resulting material (MTTZ-MCM-41) has been characterized by powder X-ray
T Matsubara et al.
Japanese journal of pharmacology, 45(3), 303-315 (1987-11-01)
The disulfiram-like effect of various beta-lactam antibiotics containing N-methyltetrazolethiol (NMTT) on the alcohol-metabolizing system was studied using rats. Their administration caused decreased activities in low Km aldehyde dehydrogenase (ALDH) and acetaldehyde oxidation in the liver, with marked depression from several
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