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Merck
CN

361585

(S)-(+)-Epichlorohydrin

98%

Synonym(s):

(S)-(+)-2-(Chloromethyl)oxirane

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About This Item

Empirical Formula (Hill Notation):
C3H5ClO
CAS Number:
Molecular Weight:
92.52
PubChem Substance ID:
UNSPSC Code:
12352005
Beilstein/REAXYS Number:
1420784
MDL number:
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SMILES string

ClC[C@@H]1CO1

InChI

1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2/t3-/m1/s1

InChI key

BRLQWZUYTZBJKN-GSVOUGTGSA-N

vapor density

3.2 (vs air)

vapor pressure

12.5 mmHg ( 20 °C)

assay

98%

optical activity

[α]20/D +34°, c = 1 in methanol

optical purity

ee: 97% (GLC)

autoignition temp.

1421 °F

expl. lim.

21 %

bp

92-93 °C/360 mmHg (lit.)

density

1.183 g/mL at 25 °C (lit.)

Application

Chiral synthon employed in the preparation of glycidyl ethers.

Regulatory Information

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Tetrahedron Asymmetry, 4, 961-961 (1993)
Jingyun Wang et al.
Biomacromolecules, 13(2), 559-564 (2012-01-20)
The stability of a paper-immobilized antibody was investigated over a range of temperatures (40-140 °C) and relative humidities (RH, 30-90%) using both unmodified filter paper and the same paper impregnated with polyamide-epichlorohydrin (PAE) as supports. Antibody stability decreased with increasing
Epichlorohydrin.
Report on carcinogens : carcinogen profiles, 12, 180-183 (2011-08-20)
M Cirri et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(1), 46-53 (2011-08-16)
A new delivery system based on drug cyclodextrin (Cd) complexation and loading into nanostructured lipid carriers (NLC) has been developed to improve ketoprofen therapeutic efficacy. The proposed strategy exploits both the solubilizing and stabilizing properties of Cds and the prolonged
Tamotsu Neda et al.
Endocrine journal, 59(3), 239-246 (2012-01-11)
Recent studies have shown colestimide, a bile acid-binding resin, to also exert a glucose-lowering effect via amelioration of insulin resistance. To evaluate the effects of colestimide on glucose metabolism and to elucidate the underlying mechanism, we conducted a 6-month, open-label

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