361658
Phentolamine methanesulfonate salt
99%
Synonym(s):
2-(N-[m-Hydroxyphenyl]-p-toluidinomethyl)imidazoline
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About This Item
Linear Formula:
C17H19N3O · CH3SO3H
CAS Number:
Molecular Weight:
377.46
EC Number:
MDL number:
UNSPSC Code:
12352200
Assay
99%
mp
180-182 °C (lit.)
SMILES string
CS(O)(=O)=O.Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
InChI
1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)
InChI key
OGIYDFVHFQEFKQ-UHFFFAOYSA-N
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Application
Useful α-adrenoceptor antagonist.
Biochem/physiol Actions
α-Adrenergic receptor antagonist; peripheral vasodilator.
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D Mohuczy-Dominiak et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 279-287 (1993-07-01)
Marked differences in the characteristics of alpha-2 adrenoceptors in the kidney of various species have been reported. In addition, there are functional differences in alpha-2 adrenoceptors in various nephron segments of the same species. In this study we have characterized
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