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361658

Phentolamine methanesulfonate salt

Name: Phentolamine methanesulfonate salt
Brand: ALDRICH

99%

Synonym(s):

2-(N-[m-Hydroxyphenyl]-p-toluidinomethyl)imidazoline

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About This Item

Linear Formula:

C₁₇H₁₉N₃O · CH₃SO₃H

CAS Number:

65-28-1

Molecular Weight:

377.46

EC Number:

200-604-6

UNSPSC Code:

12352200

MDL number:

MFCD00134201

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Properties

assay

99%

mp

180-182 °C (lit.)

SMILES string

CS(O)(=O)=O.Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3

InChI

1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)

InChI key

OGIYDFVHFQEFKQ-UHFFFAOYSA-N

Description

Application

Useful α-adrenoceptor antagonist.

Biochem/physiol Actions

α-Adrenergic receptor antagonist; peripheral vasodilator.

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Alpha-2 adrenoceptors in medullary thick ascending limbs of the rabbit kidney.

D Mohuczy-Dominiak et al.

The Journal of pharmacology and experimental therapeutics, 266(1), 279-287 (1993-07-01)

Marked differences in the characteristics of alpha-2 adrenoceptors in the kidney of various species have been reported. In addition, there are functional differences in alpha-2 adrenoceptors in various nephron segments of the same species. In this study we have characterized