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366005

5-Hydroxy-2-nitrobenzyl alcohol

Name: 5-Hydroxy-2-nitrobenzyl alcohol
Brand: ALDRICH

97%

Synonym(s):

(5-Hydroxy-2-nitrophenyl)methanol, 1-Nitro-2-hydroxymethyl-4-hydroxybenzene, 3-Hydroxymethyl-4-nitrophenol, 5-Hydroxy-2-nitrobenzenemethanol

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About This Item

Linear Formula:

HOC₆H₃(NO₂)CH₂OH

CAS Number:

60463-12-9

Molecular Weight:

169.13

NACRES:

NA.22

PubChem Substance ID:

24862599

UNSPSC Code:

12352100

MDL number:

MFCD00134308

Assay:

97%

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Properties

Quality Level

100

assay

97%

mp

111-115 °C (lit.)

functional group

hydroxyl, nitro

SMILES string

OCc1cc(O)ccc1[N+]([O-])=O

InChI

1S/C7H7NO4/c9-4-5-3-6(10)1-2-7(5)8(11)12/h1-3,9-10H,4H2

InChI key

ODWVFIWBWJXDMT-UHFFFAOYSA-N

Description

Application

5-Hydroxy-2-nitrobenzyl alcohol may be used in the synthesis of 5-(2′-(dimethylamino)ethoxy)-2-nitrobenzyl alcohol. It may be used as difunctional photo-responsive initiator in the synthesis of thermo-responsive and photo-cleavable amphiphilic block copolymers containing photodegradable linkers as junction points between hydrophilic and hydrophobic chains.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Synthesis and Characterization of Thermo-responsive and Photo-cleavable Block Copolymers as Nanocarriers.

Lee R-S, et al.

Royal Society of Chemistry Advances (2014)

Thermo-and light-regulated fluorescence resonance energy transfer processes within dually responsive microgels.

Yin J, et al.

Polym. Chem., 2(2), 363-371 (2011)

Synthesis and characterization of amphiphilic photocleavable polymers based on dextran and substituted-ɛ-caprolactone.

Ren-Shen Lee et al.

Carbohydrate polymers, 117, 201-210 (2014-12-17)

In this study, we synthesized photocleavable amphiphilic block copolymers containing photodegradable linkers, 5-hydroxy-2-nitrobenzyl alcohol, as junction points between hydrophilic dextran (or maltodextrin) and hydrophobic poly(4-substituted-ɛ-caprolactone) chains, by using a combination of ring-opening polymerization and nucleophilic substitution reactions. When the polymer

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Global Trade Item Number

SKU	GTIN
366005-5G	04061831825947