374962
4-Guanidinobenzoic acid hydrochloride
99%
Synonym(s):
4-Guanidobenzoic acid hydrochloride
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About This Item
Linear Formula:
H2NC(=NH)NHC6H4CO2H · HCl
CAS Number:
Molecular Weight:
215.64
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
255-956-3
Beilstein/REAXYS Number:
3718032
MDL number:
Assay:
99%
Form:
solid
assay
99%
form
solid
mp
285 °C (dec.) (lit.)
storage temp.
2-8°C
SMILES string
Cl[H].NC(=N)Nc1ccc(cc1)C(O)=O
InChI
1S/C8H9N3O2.ClH/c9-8(10)11-6-3-1-5(2-4-6)7(12)13;/h1-4H,(H,12,13)(H4,9,10,11);1H
InChI key
YETFLAUJROGBMC-UHFFFAOYSA-N
General description
4-Guanidinobenzoic acid hydrochloride is a guanidine derivative. Quality standard of 4-guanidinobenzoic acid hydrochloride has been investigated.
Application
4-Guanidinobenzoic acid hydrochloride may be used in ELISA inhibition assay of mouse antiserum. It may be used in the synthesis of human acrosin inhibitor 4′-acetaminophenyl 4-guanidinobenzoate hydrochloride.2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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M K Ramjee et al.
Thrombosis research, 98(6), 559-569 (2000-07-19)
Nafamostat mesilate (FUT-175), a synthetic serine protease inhibitor, is active against a number of the serine proteases involved in coagulation. This has been proposed as the basis of its anticoagulant activity. We investigated the reaction of Nafamostat with bovine pancreatic
I Midgley et al.
Xenobiotica; the fate of foreign compounds in biological systems, 24(1), 79-92 (1994-01-01)
1. The metabolic fate of N,N-dimethylcarbamoylmethyl 4-(4-guanidino[14C]benzoyloxy)phenylacetate methanesulphonate (14C-camostat mesylate) was investigated after i.v. administration to man (12-h infusion), and to rat and dog (bolus injection). 2. Renal excretion (mainly in 24 h) accounted for at least 80% dose in
Hepatic and pancreatic metabolism and biliary excretion of the protease inhibitor camostat mesilate.
K Beckh et al.
International journal of pancreatology : official journal of the International Association of Pancreatology, 10(3-4), 197-205 (1991-11-01)
The hepatic metabolism and biliary and pancreatic excretion of the serine protease inhibitor camostat mesilate and its metabolites FOY-251 and GBA were studied in rats in vivo and in in sutu liver-perfusion experiments. After oral feeding (100 mg/kg) and iv
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 374962-5G | 04061838349125 |