379700
10-Hydroxydecanoic acid
technical grade
Synonym(s):
NSC 15139
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
HO(CH2)9CO2H
CAS Number:
Molecular Weight:
188.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
216-848-1
MDL number:
InChI key
YJCJVMMDTBEITC-UHFFFAOYSA-N
InChI
1S/C10H20O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h11H,1-9H2,(H,12,13)
SMILES string
OCCCCCCCCCC(O)=O
grade
technical grade
form
solid
impurities
<15% intermolecular dilactone
mp
75-77 °C (lit.)
functional group
carboxylic acid, hydroxyl
General description
10-Hydroxydecanoic acid (10-HDA) is a saturated fatty acid of hydroxy-trans-2-decenoic acid (10H2DA). Its molecule has two functional groups (-OH and -COOH). It has been reported to prevent the lipopolysaccharide-induced NO production in murine macrophages. 10-HDA has been extracted from royal jelly obtained from honeybees (Apis mellifera) and exhibits estrogenic action. Its polymerization with the polyethylene glycol-modified lipase in a transparent benzene solution has been reported to proceed by the formation of ester linkage.
Application
10-Hydroxydecanoic acid is suitable for use in a study on Novozym 435-catalyzed condensation polymerization of cis-9,10-epoxy-18-hydroxyoctadecanoic acid and its comparison with corresponding polymerization of 10-hydroxydecanoic acid.
Reactant involved in:
- Synthesis of copolymers of acrylamide and sodium acryloyloxydecanoate
- Macrolactonization for preparation of Sansalvamide A
- Studies of chain length selectivity for cutinase catalyzed polycondensation reactions
- Ruthenium-catalyzed esterification followed by macrocyclization
- Synthesis of anhydrides and esters
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Keita Takahashi et al.
Biomedical research (Tokyo, Japan), 34(4), 205-214 (2013-09-03)
Toll-like receptors (TLRs) play a critical role in innate immunity by recognizing pathogen-associated molecular patterns. Various environmental materials including lipids may affect TLR signaling and modulate innate immune responses. We previously reported that 10-hydroxy-trans-2-decenoic acid (10H2DA) inhibits lipopolysaccharide (LPS)-induced interleukin
Polymerization of 10-hydroxydecanoic acid in benzene with polyethylene glycol-modified lipase.
Ajima A, et al.
Biotechnology Letters, 7(5), 303-306 (1985)
Kazu-Michi Suzuki et al.
Evidence-based complementary and alternative medicine : eCAM, 5(3), 295-302 (2008-10-03)
We have previously reported that royal jelly (RJ) from honeybees (Apis mellifera) has weak estrogenic activity mediated by interaction with estrogen receptors that leads to changes in gene expression and cell proliferation. In this study, we isolated four compounds from
Maroula G Kokotou et al.
Metabolites, 10(1) (2020-01-23)
The lipidome of royal jelly (RJ) consists of medium-chained (8-12 carbon atoms) free fatty acids. We present herein a liquid chromatography-high resolution mass spectrometry (HRMS) method that permits the determination of RJ fatty acids and at the same time the
Martin T Gaugg et al.
Journal of breath research, 11(4), 046004-046004 (2017-09-14)
We explore whether real-time breath analysis by high resolution mass spectrometry is suitable to monitor changes at the metabolic level due to inhaling bronchodilator medication. We compared the breath levels of metabolites in a group of patients (n = 50) at baseline
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service