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Merck
CN

38534

Polylactic acid

Mw ~60,000

Synonym(s):

Poly(2-hydroxypropionic acid)

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About This Item

CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
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form

solid

Quality Segment

shelf life

limited shelf life, expiry date on the label

mol wt

Mn ~30,000, Mw ~60,000

SMILES string

[O-]C(=O)C(O)C.[H+]

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

InChI key

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

General description

Polylactic acid(PLA) is a biodegradable polyester synthesized from lactic acid monomer via ring opening polymerization. Owing to its excellent thermal, mechanical and barrier properties, it is widely used in the field of tissue engineering, drug delivery, and orthopedic devices.

Application

Polylactic acid can be used to prepare tubular scaffolds via the electrospinning method. These scaffolds are applicable in vascular tissue engineering.

It can be used to prepare PLA/polyvinyl alcohol wound dressing membrane through electrospinning and coating method. The coating of PLA improves the mechanical strength of nanofiber and acts as a protective layer to control the release of drug to the wound site.

It can also be used to synthesize free-standing, flexible ultra-thin PLA nanofilms which can act as a matrix for adhesion, spreading, and proliferation of skeletal muscle cells.

Features and Benefits

  • Biocompatibility
  • Lower toxicity
  • Low cost
  • Better encapsulation


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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