393711
2′,3′-Dideoxy-3′-fluorouridine
95%
Synonym(s):
3′-Fluoro-2′,3′-dideoxyuridine
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About This Item
Empirical Formula (Hill Notation):
C9H11FN2O4
CAS Number:
Molecular Weight:
230.19
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
415-360-8
Beilstein/REAXYS Number:
6064366
MDL number:
assay
95%
optical activity
[α]20/D +10.5°, c = 0.5 in 1 M NaOH
mp
184-188 °C (lit.)
SMILES string
OC[C@H]1O[C@H](C[C@@H]1F)N2C=CC(=O)NC2=O
InChI
1S/C9H11FN2O4/c10-5-3-8(16-6(5)4-13)12-2-1-7(14)11-9(12)15/h1-2,5-6,8,13H,3-4H2,(H,11,14,15)/t5-,6+,8+/m0/s1
InChI key
BKIUEHLYJFLWPK-SHYZEUOFSA-N
General description
2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.
Application
2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:
- 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.
- 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.
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