393797
3-Amino-5-phenylpyrazole
98%
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
Empirical Formula (Hill Notation):
C9H9N3
CAS Number:
Molecular Weight:
159.19
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
98%
mp
124-127 °C (lit.)
functional group
phenyl
SMILES string
Nc1cc([nH]n1)-c2ccccc2
InChI
1S/C9H9N3/c10-9-6-8(11-12-9)7-4-2-1-3-5-7/h1-6H,(H3,10,11,12)
InChI key
PWSZRRFDVPMZGM-UHFFFAOYSA-N
General description
3-Amino-5-phenylpyrazole (3-phenyl-1H-pyrazol-5-amine), an amino pyrazole derivative, is an aza-heterocyclic amine. It has been reported to be synthesized by heating either 3-amino-4-bromo- or 3-amino-5-phenylisothiazole in the presence of anhydrous hydrazine. On reaction with ZnCl2 it affords chlorido-tris(3-amino-5-phenyl-1Hpyrazole-N2)zinc (II) chloride.
Application
3-Amino-5-phenylpyrazole ((3-phenyl-1H-pyrazol-5-amine) may be used in the synthesis of the following:
- Urea derivatives by reaction with azido(6-(benzofuran-2-yl)-2-methylpyridin-3-yl) methanone.
- 2-Mercaptoacetamide analogs by treating with thioglycolic acid.
- 3-(Substituentpyrimidayl)-5,6-benzocoumarins by treating with 3-(2′-formyl-1′-chlorovinyl)-5,6-benzocoumarin.
- Substituted 2,7-diphenylpyrazolo[1,5-a]pyrimidine-5-carboxylic esters by reacting with substituted β-diketo esters.
- N-ethoxycarbonylthiourea derivative by reacting with ethoxycarbonyl isothiocyanate.
- Heterobiaryl pyrazolo[3,4-b]pyridines by reacting with indole-3-carboxaldehyde.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
The conversion of isothiazoles into pyrazoles using hydrazine.
Ioannidou HA and Koutentis PA
Tetrahedron, 65(34), 7023-7037 (2009)
Crystal structure of chlorido-tris (3-amino-5-phenyl-1H pyrazole-N2) zinc (II) chloride, [ZnCl (C9H9N3)3] Cl.
Jacimovic ZK, et al
Zeitschrift fur Kristallographie, 226(3), 397-399 (2011)
Syntheses of 3-pyrimidyl-and 3-pyranyl-5, 6-benzocoumarin derivatives.
El-Deen IM, et al
Bull. Korean Chem. Soc., 23(4), 610-612 (2002)
Convenient synthesis of some new pyrazolo [5, 1-c] triazines, isoxazolo [3, 4-d] pyrimidine and pyridine derivatives containing benzofuran moiety.
Abdelhamid AO, et al
European Journal of Chemistry, 3(2), 129-137 (2012)
Recent advances in the chemistry of ethoxycarbonyl isothiocyanate and related compounds.
George B and Papadopoulos EP
Journal of Heterocyclic Chemistry, 20(5), 1127-1142 (1983)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service