393835
o-Xylylene N,N-diethylphosphoramidite
technical grade
Synonym(s):
3-(Diethylamino)-1,5-dihydro-2,4,3-benzodioxaphosphepine
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About This Item
Empirical Formula (Hill Notation):
C12H18NO2P
CAS Number:
Molecular Weight:
239.25
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3590087
Form:
liquid
grade
technical grade
Quality Level
form
liquid
refractive index
n20/D 1.541 (lit.)
bp
95-96 °C/0.1 mmHg (lit.)
solubility
THF: soluble, acetonitrile: soluble, cold water: insoluble, dichloromethane: soluble
density
1.109 g/mL at 25 °C (lit.)
functional group
amine
SMILES string
CCN(CC)P1OCc2ccccc2CO1
InChI
1S/C12H18NO2P/c1-3-13(4-2)16-14-9-11-7-5-6-8-12(11)10-15-16/h5-8H,3-4,9-10H2,1-2H3
InChI key
JDAKPBBWYIWXJF-UHFFFAOYSA-N
Application
o-Xylylene N,N-diethylphosphoramidite (N,N-diethyl-1,5-dihydro-2,4,3-benzodioxaphosphepin-3-amine) may be used in the synthesis of the following:
- bicyclic glycosyl phosphite
- pentakis(o-xylylene phosphate)
- o-xylylene alkyl phosphites
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Synergistic inhibition of human Synergistic inhibition of human α-1, 3-fucosyltransferase V.
Qiao L, et al
Journal of the American Chemical Society, 118(33), 7653-7662 (1996)
Honglu Zhang et al.
Organic letters, 11(7), 1551-1554 (2009-03-04)
The phosphorylated inositol diphosphates, including the diphosphoinositol pentakisphosphate regioisomers, play critical roles in signal transduction and cellular regulation. In particular, the IP(7) isomer 5-PP-Ins(1,2,3,4,6)P(5) is implicated in a nonenzymatic phosphate transfer converting a protein serine phosphate residue to a serine
Utilization of O-xylylene N,N-diethylphosphoramidite for the synthesis of phosphoric diesters.
Watanabe Y, et al
Tetrahedron Letters, 33(10), 1313-1316 (1992)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 393835-1G | 04061838097903 |
| 393835-5G | 04061838090584 |