401633
1-Pyrenemethylamine hydrochloride
95%
Synonym(s):
PMA
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About This Item
Empirical Formula (Hill Notation):
C17H13N · HCl
CAS Number:
Molecular Weight:
267.75
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Product Name
1-Pyrenemethylamine hydrochloride, 95%
InChI
1S/C17H13N.ClH/c18-10-14-7-6-13-5-4-11-2-1-3-12-8-9-15(14)17(13)16(11)12;/h1-9H,10,18H2;1H
SMILES string
Cl[H].NCc1ccc2ccc3cccc4ccc1c2c34
InChI key
RGNMXKKNDSHTFD-UHFFFAOYSA-N
assay
95%
form
powder
mp
258 °C (dec.) (lit.)
functional group
amine
Quality Level
Related Categories
Application
1-Pyrenemethylamine (PyNH2) has also been used for the synthesis of:
It can also be used for the synthesis of 4,6-dichloro-2-pyrenemethylamine-1,3,5-triazine, a precursor to synthesize a star shaped polymer 4,6-bis(9H-carbazol-2-yloxy)-2-(pyrenemethylamine)-1,3,5 triazine (TPC).
- Pyrenyl hyaluronan (Py-HA), a pyrenyl-based polymer that can be used for the development of pH-triggered drug carriers.
- An electrochemical electrode of reduced graphene oxide bound with pyrene functionalized folic acid derivative.
It can also be used for the synthesis of 4,6-dichloro-2-pyrenemethylamine-1,3,5-triazine, a precursor to synthesize a star shaped polymer 4,6-bis(9H-carbazol-2-yloxy)-2-(pyrenemethylamine)-1,3,5 triazine (TPC).
1-Pyrenemethylamine hydrochloride (PyNH2) has been used for the loading of human telomerase reverse transcriptase (hTERT) small interfering RNA (siRNA) to the functionalized graphene oxide (GO) for the tumor targeting delivery of siRNA.
1-Pyrenemethylamine hydrochloride has been used in the preparation of 1-pyrenemethylamine. It may be used for the noncovalent functionalization of SWNTs with cationic moieties which binds strongly to the negatively charged phosphate backbone of the DNA. It may be used in the preparation of the following Schiff-base ligand:
- pyren-1-ylmethyl-[2-(6-{2-[(pyren-1-ylmethylimino)-methyl]-phenoxymethyl}-pyridin-2-ylmethoxy)-benzylidene]-amine
- 2(pyren-1-ylmethyl-{2-[6-(2-{[(pyren-1-ylmethyl)-amino]-methyl}- phenoxymethyl)-pyridin-2-ylmethoxy])-benzyl}-amine
General description
1-Pyrenemethylamine hydrochloride is an organic building block.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Assembly of chemically reduced graphene oxide with folic acid functionalized with pyrene moieties and electrochemical sensing of folate receptors.
Kwon B, et al.
Carbon Letters, 27(2), 26-34 (2018)
Liwei Hui et al.
ACS nano, 14(10), 13047-13055 (2020-10-14)
We demonstrate area-selective atomic layer deposition (ALD) of oxides on DNA nanostructures. Area-selective ALD of Al2O3, TiO2, and HfO2 was successfully achieved on both 2D and 3D DNA nanostructures deposited on a polystyrene (PS) substrate. The resulting DNA-inorganic hybrid structure
Intramolecular excimer formation and sensing behavior of new fluorimetric probes and their interactions with metal cations and barbituric acids.
Lodeiro C, et al.
Sensors and Actuators B, Chemical, 115(1), 276-286 (2006)
The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA.
Yang X, et al.
Journal of Materials Chemistry, 22(14), 6649-6654 (2012)
Reactively formed block and graft copolymers as compatibilizers for polyamide 66/PS blends.
Jeon HK, et al.
Polymer, 45(1), 197-206 (2004)
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