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Merck
CN

407453

(S)-(+)-Norepinephrine L-bitartrate

99%

Synonym(s):

(+)-α-(Aminomethyl)-3,4-dihydroxybenzyl alcohol (+)-tartrate (1:1), D-Noradrenaline L-bitartrate, D-Noradrenaline hydrogen L-tartrate, D-Norepinephrine D-bitartrate

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About This Item

Linear Formula:
(HO)2C6H3CH(CH2NH2)OH · C4H6O6
CAS Number:
Molecular Weight:
319.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
211-268-5
MDL number:
Assay:
99%
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InChI key

WNPNNLQNNJQYFA-HQWYAZORSA-N

InChI

1S/C8H11NO3.C4H6O6/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-;1-,2-/m11/s1

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.NC[C@@H](O)c1ccc(O)c(O)c1

assay

99%

optical activity

[α]20/D +38°, c = 1 in H2O

mp

166 °C (dec.) (lit.)

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Studies have reported that railway noise causes stress responses. To evaluate the effects of high-speed railway (HSR) noise on behaviors and plasma monoamines. Institute of cancer research mice were exposed to previously recorded HSR noise for 53 days. The noise
[Tapentadol prolonged release for severe chronic pain. Results of a non-interventional study involving general practitioners and internists].
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MMW Fortschritte der Medizin, 155(1), 64-64 (2013-04-12)
Martin Desseilles
Sante mentale au Quebec, 37(2), 107-127 (2013-05-15)
In general, it appears that the suicidal act is highly unpredictable with the current scientific means available. In this article, the author submits the hypothesis that predicting suicide is complex because it results in predicting a choice, in itself unpredictable.
Mood disorders: the dark night.
Sarah DeWeerdt
Nature, 497(7450), S14-S15 (2013-05-24)
Wataru Inoue et al.
Nature neuroscience, 16(5), 605-612 (2013-04-09)
Exposure to a stressor sensitizes behavioral and hormonal responses to future stressors. Stress-associated release of noradrenaline enhances the capacity of central synapses to show plasticity (metaplasticity). We found noradrenaline-dependent metaplasticity at GABA synapses in the paraventricular nucleus of the hypothalamus

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