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Merck
CN

408468

Boc-Asp-OH

99%

Synonym(s):

N-(tert-Butoxycarbonyl)-L-aspartic acid, Boc-L-aspartic acid

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About This Item

Linear Formula:
(CH3)3COCONHCH(COOH)CH2COOH
CAS Number:
13726-67-5
Molecular Weight:
233.22
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
24865571
EC Number:
237-294-7
Beilstein/REAXYS Number:
1913973
MDL number:
MFCD00037279

Key Documents

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InChI key

KAJBMCZQVSQJDE-YFKPBYRVSA-N

InChI

1S/C9H15NO6/c1-9(2,3)16-8(15)10-5(7(13)14)4-6(11)12/h5H,4H2,1-3H3,(H,10,15)(H,11,12)(H,13,14)/t5-/m0/s1

SMILES string

CC(C)(C)OC(=O)N[C@@H](CC(O)=O)C(O)=O

assay

99%

form

solid

optical activity

[α]20/D −6.0°, c = 1 in methanol

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

116-118 °C (lit.)

application(s)

peptide synthesis

Gene Information

human ... CA1(759), CA2(760)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
09919TE
00527ME
15622CU
09706EF
07112PR

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Chaitanya R Joshi et al.
Molecular therapy. Nucleic acids, 12, 645-657 (2018-08-07)
Astrocytes, the "star-shaped" glial cells, are appealing gene-delivery targets to treat neurological diseases due to their diverse roles in brain homeostasis and disease. Cationic polymers have successfully delivered genes to mammalian cells and hence present a viable, non-immunogenic alternative to
Mintai P Hwang et al.
Journal of controlled release : official journal of the Controlled Release Society, 318, 270-278 (2019-12-24)
Melanoma is the deadliest type of skin cancer with one of the fastest increasing incidence rates among solid tumors. The use of checkpoint inhibitors (e.g. αPD-1 antibody) has recently emerged as a viable alternative to conventional modes of therapy. However
Yin-Chih Fu et al.
Acta biomaterialia, 10(11), 4583-4596 (2014-07-23)
Nanoparticles (NP) that target bone tissue were developed using PLGA-PEG (poly(lactic-co-glycolic acid)-polyethylene glycol) diblock copolymers and bone-targeting moieties based on aspartic acid, (Asp)(n(1,3)). These NP are expected to enable the transport of hydrophobic drugs. The molecular structures were examined by

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