411779
N-tert-Butylacrylamide
97%
Synonym(s):
N -(1,1-Dimethylethyl)-2-propenamide, N -t -Butylacrylamide
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About This Item
Linear Formula:
CH2=CHCONHC(CH3)3
CAS Number:
Molecular Weight:
127.18
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-505-6
Beilstein/REAXYS Number:
1742331
MDL number:
Product Name
N-tert-Butylacrylamide, 97%
InChI key
XFHJDMUEHUHAJW-UHFFFAOYSA-N
InChI
1S/C7H13NO/c1-5-6(9)8-7(2,3)4/h5H,1H2,2-4H3,(H,8,9)
SMILES string
CC(C)(C)NC(=O)C=C
assay
97%
form
solid
mp
126-129 °C (lit.)
Quality Level
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Application
nTBA is temperature sensitive monomers that can be potentially used in drug delivery systems, dewatering of proteins, and immobilization of cells. It can be used in the preparation of poly(nTBA) based copolymeric hydrogels for bovin serum albumin.
General description
N-tert-Butylacrylamide (nTBA) belongs to the class of hydrophobic acrylamides which can be synthesized by Ritter reaction and optimized by using N-tert-butyl acetate and acetic acid.
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An efficient and scalable ritter reaction for the synthesis of tert-butyl amides
Baum JC, et al.
The Journal of Organic Chemistry, 74(5), 2207-2209 (2009)
Graft copolymerization onto starch-I. Synthesis and optimization of starch grafted with N-tert-butylacrylamide copolymer and its hydrogels
Fares MM, et al.
Journal of Polymer Research, 10(2), 119-125 (2003)
Shuai Yu et al.
Biomedical optics express, 11(3), 1517-1538 (2020-03-25)
Ultrasound-switchable fluorescence (USF) is a novel imaging technique that provides high spatial resolution fluorescence images in centimeter-deep biological tissue. Recently, we successfully demonstrated the feasibility of in vivo USF imaging using a frequency-domain photomultiplier tube-based system. In this work, for
pH/Temperature-Sensitive Imprinted Ionic Poly (N-tert-butylacrylamide-co-acrylamide/maleic acid) Hydrogels for Bovine Serum Albumin
Demirel G, et al.
Macromolecular Bioscience, 5(10), 1032-1037 (2005)
Hossein Hosseinzadeh et al.
International journal of biological macromolecules, 113, 859-868 (2018-03-11)
In the present work, a novel magnetic chitosan/graphene oxide nanocomposite (MCGON) was synthesized for the removal of Cu2+ from aqueous solutions. The adsorbent was composed of graphene oxide (GO) modified by ethylenediamine (ED), Fe3O4 nanoparticles and chitosan-g-poly(acrylic acid-co-2-acrylamido-2-methylpropane sulfonic acid)
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