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Merck
CN

412554

Sigma-Aldrich

(R)-(+)-1,2-Diaminopropane dihydrochloride

99%

Synonym(s):

(R)-(+)-Propylenediamine dihydrochloride, 1,2-Propanediamine dihydrochloride

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About This Item

Linear Formula:
CH3CH(NH2)CH2NH2·2HCl
CAS Number:
Molecular Weight:
147.05
Beilstein:
5740937
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
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Assay

99%

optical activity

[α]20/D +4.0°, c = 20 in H2O

mp

241-244 °C (lit.)

functional group

amine

SMILES string

Cl[H].Cl[H].C[C@@H](N)CN

InChI

1S/C3H10N2.2ClH/c1-3(5)2-4;;/h3H,2,4-5H2,1H3;2*1H/t3-;;/m1../s1

InChI key

AEIAMRMQKCPGJR-HWYNEVGZSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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G Auling et al.
Applied and environmental microbiology, 57(12), 3585-3592 (1991-12-01)
Polyphosphate-accumulating gram-negative bacteria were isolated from different anaerobic-aerobic activated sludge systems with diverse processes for enhanced biological phosphorus (P) elimination. Of 22 isolates, 10 were allocated to the genus Acinetobacter by using multiple-test systems and soluble protein and polyamine patterns.
Lorin A Thompson et al.
Bioorganic & medicinal chemistry letters, 21(22), 6909-6915 (2011-10-07)
The synthesis, evaluation, and structure-activity relationships of a set of related constrained diaminopropane inhibitors of BACE-1 are described. The full in vivo profile of an optimized inhibitor in both normal and P-gp deficient mice is compared with data generated in
M A Medina et al.
The Biochemical journal, 280 ( Pt 3), 825-827 (1991-12-15)
1. L-Ornithine transport by plasma-membrane vesicles isolated from Ehrlich cells is Na(+)-independent and shows a saturable and a diffusional component. 2. Putrescine, histamine, 5-hydroxytryptamine and 2,3-diaminopropane at 55 microM concentration significantly inhibit 0.5 mM-L-ornithine transport at least for the first
Chiral cyanide-bridged Mn(II)Mn(III) ferrimagnets, [Mn(II)(HL)(H2O)][Mn(III)(CN)6].2H2O (L = S- or R-1,2-diaminopropane): syntheses, structures, and magnetic behaviors.
Wakako Kaneko et al.
Journal of the American Chemical Society, 129(2), 248-249 (2007-01-11)
K Hamana et al.
Microbios, 103(404), 43-51 (2000-10-18)
Cellular levels of diaminopropane, putrescine and cadaverine, and decarboxylase activities to produce these diamines in six species (16 strains) of Haemophilus and four species (5 strains) of Actinobacillus belonging to the family Pasteurellaceae of the gamma subclass of the class

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